Structure of PDB 6ke6 Chain RF Binding Site BS01

Receptor Information
>6ke6 Chain RF (length=241) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IEDISAMKNGFIVVPFKLPDHKALPASLHFMFAKRHQSSNSNESDCLFLV
NLPLLSNIEHMKKFVGQLCGKYDTVSHVEELLYNDEFGLHEVDLSALTSD
LMSSPRNTALLKFVDAASINNCWNALKKYSNLHAKHPNELFEWTYTTPSF
TTFVNFYKPLDIDYLKEDIHTHMAIFEQREAQAQEDVQSSIVDEDGFTLV
VGKNTKSLNSIRKKILNKNKKAKKDFYRFQVRERKKQEINQ
Ligand information
>6ke6 Chain SA (length=1310) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agauaguuaucugguugauccugccaguagucauaugcuugucucagcca
ugcaugucuaaguauaagcaauuuauacagugaaacugcgaaggcucauu
aaaucaguuaucguuuauuugauaguuccaugguauaacugugguaauuc
uagagcuaauacaugcuaaucucgacccuuuggaagagauguauuuauua
gaucaaugucuucggacucuuugaugaaauaacuuuucgaaucgcauggc
cuugugcuggcgaugguucauucaaauuucugcccuaucaacuuucgaug
guaggauaguggccuaccaugguuucaacggguaacggggaauaaggguu
cgauuccggagagggagccugagaaacggcuaccacauccaaggaaggca
gcaggccaaauuacccaauccuaauucagggagguagugacaauaaauaa
cgauacagggcccauucgggucuuguaauuggaaugaguacaauguaaau
accuuaacgaggaacaauuggagggcaagucuggugccagcagccgcggu
aauuccagcuccaauagcguauauuaaaguuguugcagaagcucguaguu
gaacuggcccgguuggccgguccggauuuccaacggggccuugauuaaua
gggacggucgggggcaucaguauucaauugucagaggugaaauucuugga
uuuauugaagacuaacuacugcgaaagcauuugccaaggacguuuucauu
aaucaagaacgaccauaaacuaugccgacuagggaucgggugguguuuuu
uuaaugacccacucggcaccuuacgagaacuggggggaguauggucgcaa
ggcugaaacuuaaaggaauugacggaagggcaccaccaggaguggagccu
gcggcucaacacggggaaacucaccagguccagacacaauaaggauugac
auucuugauuuugugggugguggugcauugaugcccuuguucugggccac
gcgcgcuacacugacggagccagcgagucuaaccuuggccgagaggucuu
gguaaucuugugaaacuccgucgugcuggggauauucaacgaggaauucc
uaguaagcgcaagucaucagcuugcguugauuacgucccugcccuuugua
cacaccgcccgucgcuaguaccgauugaauggcuuagugaggccucagga
ucugcuuagagaagggggcaacuccaucucagagcggagaauuuggacaa
acuuggucauuuagaggaacuaaaagucguaacaagguuuccguagguga
accugcggaa
...........................<<<<.<<<<<<...<....<<<.
<<...<<....<<....<<..........>>...>>.>>.....<<<...
....<<<..<<..<<....<<<..........<....<<<.<<<.....>
>>.>>.>....>.......<<<<............>>>>.....<<<<<.
..<<<<.<........>...>>>>...>>>>>.........<<<<..<<<
.....>>>.>>>>....>>>...>>>>..>>>.<.<....<<<....<<<
<<<<<.......>>>>>>>>>>>......>.>.....<<...........
....>>..>>>.<<.<<<..........>>>.>>...<<....>>.....
.>>>>>......<<<....<<<.....>>>..>>>.........>.....
<<<<<<<.<<<<<....>>>>>.>>>.>>>>......<<..<........
...>..>>.........<<<<<<.......<<<....>>>..........
........>>>>>>..>>>>>>>>>>..............<.<<...<<<
.<<..<<<<<.<<<<<..<.......>..>>>>>.>>>>>....>>....
<<<<<<.<<...<<<<..<<..<<<<<<.<...<<<......>>>.....
.>.>>>>>>..>>.......<<....>>...>>>>..>.>>>>.>>>...
>>>...>>.>...............<<...<<<..<<<<<<<<.<<<...
.....>>>>>>>>>>>..>>>..>>.........................
..<<.........>>.....<<<<<<<<<<<<..<<.<<<<<<..<<<.<
<<<.......................<<......<<<<<...........
..........>>>>>......<<<........>>>.....>>.......>
>>>.>>>.....<<<<<<<............<<<..<<<<....>>>>..
>>>............>>>>>>>.......................>>>>>
>....<<<<<<<<.......>>>>>>>>......>>...>>>>>>>....
........>>>>>..<<<<.<<.....<<<<<<<.<<<..<.<<......
<<<<<<<...<<.<<<<....>>>>.>>...>>>>>>>......>>.>..
>>>.>>>>>>>....>>.>>>>................<<<<<<<<<...
.>>>>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6ke6 3.4 angstrom cryo-EM structure of yeast 90S small subunit preribosome
Resolution3.4 Å
Binding residue
(original residue number in PDB)		K218 N219 T220 S225 K228 K229 K233
Binding residue
(residue number reindexed from 1)		K203 N204 T205 S210 K213 K214 K218
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
GO:0042790 nucleolar large rRNA transcription by RNA polymerase I
GO:0060962 regulation of ribosomal protein gene transcription by RNA polymerase II
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0032040 small-subunit processome
GO:0032545 CURI complex
GO:0034456 UTP-C complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6ke6, PDBe:6ke6, PDBj:6ke6
PDBsum6ke6
PubMed
UniProtP25368|RRP7_YEAST Ribosomal RNA-processing protein 7 (Gene Name=RRP7)

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