Structure of PDB 4tue Chain R4 Binding Site BS01

Receptor Information

>4tue Chain R4 (length=71) Species: 300852 (Thermus thermophilus HB8)

MKEGIHPKLVPARIICGCGNVIETYSTKPEIYVEVCSKCHPFYTGQQRFV
DTEGRVERFQRRYGDSYRKGR

Ligand information

>4tue Chain QA (length=1500)

uggagaguuugauccuggcucagggugaacgcuggcggcgugccuaagac
augcaagucgugcgggccgcggggucuccguggucagcggcggacgggug
aguaacgcgugggugaccuacccggaagagggggacaacccggggaaacu
cgggcuaaucccccauguggacccgccccuugggguguguccaaagggcu
uugcccgcuuccggaugggcccgcgucccaucagcuaguuggugggguaa
uggcccaccaaggcgacgacggguagccggucugagaggauggccggcca
caggggcacugagacacgggccccacuccuacgggaggcagcaguuagga
aucuuccgcaaugggcgcaagccugacggagcgacgccgcuuggaggaag
aagcccuucgggguguaaacuccugaacccgggacgaaacccccgacgag
gggacugacgguaccgggguaauagcgccggccaacuccgugccagcagc
cgcgguaauacggagggcgcgagcguuacccggauucacugggcguaaag
ggcguguaggcggccuggggcgucccaugugaaagaccacggcucaaccg
ugggggagcgugggauacgcucaggcuagacggugggagaggguggugga
auucccggaguagcggugaaaugcgcagauaccgggaggaacgccgaugg
cgaaggcagccaccugguccacccgugacgcugaggcgcgaaagcguggg
gagcaaaccggauuagauacccggguaguccacgcccuaaacgaugcgcg
cuaggucucugggucuccugggggccgaagcuaacgcguuaagcgcgccg
ccuggggaguacggccgcaaggcugaaacucaaaggaauugacgggggcc
cgcacaagcgguggagcaugugguuuaauucgaagcaacgcgaagaaccu
uaccaggccuugacaugcuagggaacccgggugaaagccuggggugcccc
gcgaggggagcccuagcacaggugcugcauggccgucgucagcucgugcc
gugagguguuggguuaagucccgcaacgagcgcaacccccgccguuaguu
gccagcgguucggccgggcacucuaacgggacugcccgcgaaagcgggag
gaaggaggggacgacgucuggucagcauggcccuuacggccugggcgaca
cacgugcuacaaugcccacuacaaagcgaugccacccggcaacggggagc
uaaucgcaaaaaggugggcccaguucggauuggggucugcaacccgaccc
caugaagccggaaucgcuaguaaucgcggaucagccaugccgcggugaau
acguucccgggccuuguacacaccgcccgucacgccaugggagcgggcuc
uacccgaagucgccgggagccuacgggcaggcgccgaggguagggcccgu
gacuggggcgaagucguaacaagguagcuguaccggaaggugcggcugga

....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..<<<
.<<<..<<<..<<.<<<<<<<<<...>>>>>>>>>.>>>>>......<<.
......<<<<<<<<..<<...<<<<<<<.<<<<<....<<<<<......>
>>>>.....>>>>>...<<<<<.<<<<<....>>>>>.>>>>>..<<<<.
..>>>>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<<<<<....
...>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>
>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>>>>...
.....<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<....
..<<<<....>>>>.....>>>>....<<<<<........<<<<.....>
>>>..........>>>>>......<<<<<(((...<<<<<.....<<.))
)>>.......>>>>>>>>>>..>>>>>>>>>..........<<<((....
.<<<<...<<<.<<<<<<<.<<<<<<<<<<......<<<<<<.....>>>
>>>....>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<<<...
.<<<<<<<.<..<<<......>>>.....>.>>>>>>>...........<
<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<<<.
..<<...<<<<.<.....>.>>>>...>>>>>>>>..........<<<<<
<..<<<<<<<<<<...>>>>>>>>>>...<<..))>>.....>>>>>>.>
>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<.<<<<<
<<.<<.<<<<<<..<<<<<<<<<<......<<........>>........
..<<<<<<<......<<<<<<<<..<<<<<<<....>>>>>>>...<<<<
....>>>>..>>>>>>>>.<<<.<<<..<<<<<<.......<<<<<<<<<
....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<<..
.<...<<<.....>>>.>....>>>>>>>.....<<<<<....>>>>>..
......>>>>.........>>>...>>>>>>>>>...>>>>>>>...>>.
>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>..>>
....>>>.....>>>>>>>......<....<<<<<<<........>>>>>
>>....>.....>>>>>>....<<<<<<<..........>>>>>>>....
..>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<<<
<<<<<...<.<<<<....<<<....>>>.>>>>.>..>>>>>>>>>>>>>
..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>>>>>>...

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4tue Structural insights into translational recoding by frameshift suppressor tRNASufJ.
• Resolution: 3.5 Å
• Binding residue (original residue number in PDB): R58 Y67 R71
• Binding residue (residue number reindexed from 1): R58 Y67 R71

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding
• GO:0046872 metal ion binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4tue, PDBe:4tue, PDBj:4tue
• PDBsum: 4tue
• PubMed: 25352689
• UniProt: Q5SJE1|RL31_THET8 Large ribosomal subunit protein bL31 (Gene Name=rpmE)