Structure of PDB 8zps Chain R Binding Site BS01

Receptor Information
>8zps Chain R (length=289) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QLVHQLKGLIVLLYSVVVVVGLVGNCLLVLVIARVRRLHNVTNFLIGNLA
LSDVLMCTACVPLTLAYAFEPRGWVFGGGLCHLVFFLQPVTVYVSVFTLT
TIAVDRYVVLVHPLRRRISLRLSAYAVLAIWALSAVLALPAAVHTYHVEL
KPHDVRLCEEFWGSQERQRQLYAWGLLLVTYLLPLLVILLSYVRVSVKLR
NRVADWDRARRRRTFCLLVVIVVVFAVCWLPLHVFNLLRDLDPHAIDPYA
FGLVQLLCHWLAMSSACYNPFIYAWLHDSFREELRKLLV
Ligand information
>8zps Chain L (length=20) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
TPDINPAWYASRGIRPVGRF
Receptor-Ligand Complex Structure
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PDB8zps Molecular mechanism of prolactin-releasing peptide recognition and signaling via its G protein-coupled receptor.
Resolution2.97 Å
Binding residue
(original residue number in PDB)		Q54 T117 Y120 P142 V145 Y146 P205 E212 Y225 L229 R301 P310 Q317 H321
Binding residue
(residue number reindexed from 1)		Q1 T64 Y67 P89 V92 Y93 P152 E159 Y172 L176 R239 P248 Q255 H259
External links
PDB RCSB:8zps, PDBe:8zps, PDBj:8zps
PDBsum8zps
PubMed39223120
UniProtP49683|PRLHR_HUMAN Prolactin-releasing peptide receptor (Gene Name=PRLHR)

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