Structure of PDB 8y52 Chain R Binding Site BS01

Receptor Information
>8y52 Chain R (length=299) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LCAIYITYAVIISVGILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLL
LLTCVPVDATHYLAEGWLFGRIGCKVLSFIRLTSVGVSVFTLTILSADRY
KAVVKPLERQPSNAILKTCVKAGCVWIVSMIFALPEAIFSNVYTFRDPNK
NMTFESCTSYPVSKKLLQEIHSLLCFLVFYIIPLSIISVYYSLIARTLYK
STLNIPTEEQSHARKQIESRKRIARTVLVLVALFALCWLPNHLLYLYHSF
TSQTYVDPSAMHFIFTIFSRVLAFSNSCVNPFALYWLSKSFQKHFKAQL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8y52 Structural insights into ligand recognition, selectivity, and activation of bombesin receptor subtype-3.
Resolution2.9 Å
Binding residue
(original residue number in PDB)
T106 H107 G112 W113 S124 R127 E182 D193 F200 E201 S202 C203 S205 W284 N287 Y291 D303 S305 F309 R316
Binding residue
(residue number reindexed from 1)
T60 H61 G66 W67 S78 R81 E136 D147 F154 E155 S156 C157 S159 W238 N241 Y245 D257 S259 F263 R270
External links
PDB RCSB:8y52, PDBe:8y52, PDBj:8y52
PDBsum8y52
PubMed39024101
UniProtP32247|BRS3_HUMAN Bombesin receptor subtype-3 (Gene Name=BRS3)

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