Structure of PDB 8wul Chain R Binding Site BS01
Receptor Information
>8wul Chain R (length=274) Species:
9606
(Homo sapiens) [
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GSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEDGSHTIQIMYG
CDVGPDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAA
HAAEQQRAYLEGRCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRW
Ligand information
>8wul Chain T (length=9) Species:
9606
(Homo sapiens) [
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VVGAVGVGK
Receptor-Ligand Complex Structure
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PDB
8wul
Identification and affinity enhancement of T-cell receptor targeting a KRASG12V cancer neoantigen
Resolution
2.36 Å
Binding residue
(original residue number in PDB)
Y7 Y9 E63 D77 Y84 Y99 R114 D116 T143 K146 W147 Q155 Q156 Y159 W167
Binding residue
(residue number reindexed from 1)
Y7 Y9 E63 D77 Y84 Y99 R114 D116 T143 K146 W147 Q155 Q156 Y159 W167
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:8wul
,
PDBe:8wul
,
PDBj:8wul
PDBsum
8wul
PubMed
38684865
UniProt
A0A583ZB34
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