Structure of PDB 8tj5 Chain R Binding Site BS01

Receptor Information
>8tj5 Chain R (length=800) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKGANKKLNELLESSDNLPSASSELGSIQVSINELRRRVFQLRSKNKASK
DYTKAHYLLANSGLSFEDVDAFIKDLQTNQFLEPNPPKIIESEELEFYIR
TKKEENILMSIEQLLNGATKDFDNFINHNLNLDWAQHKNEVMKNFGILIQ
DKKTVDHKSRLNVNENNILREKFENYARIVFQFNNSRQANGNFDIANEFI
SILSSANGTRNAQLLESWKILESMKSKDINIVEVGKQYLEQQFLQYTDNL
YKKNMNEGLATNVNKIKSFIDTKLKKADKSWKISNLTVINGVPIWALIFY
LLRAGLIKEALQVLVENKANIKKVEQSFLTYFKAYASSKDHGLPVEYSTK
LHTEYNQHIKSSLDGDPYRLAVYKLIGRCDLSRKNIPAVTLSIEDWLWMH
LMLIKEKDAENDPVYERYSLEDFQNIIISYGPSRFSNYYLQTLLLSGLYG
LAIDYTYTFSEMDAVHLAIGLASLKLFKIDSSTRLTKKPKRDIRFANILA
NYTKSFRYSDPRVAVEYLVLITLNEGPTDVELCHEALRELVLETKEFTVL
LGKIGRDGARIPGVIEERQPLLHVRDEKEFLHTITEQAARRADEDGRIYD
SILLYQLAEEYDIVITLVNSLLSDTLSASDLDQPLVGPDDNSETNPVLLA
RRMASIYFDNAGISRQIHVKNKEICMLLLNISSIRELYFNKQWQETLSQM
ELLDLLPFSDELSARKKAQDFSNLDDNIVKNIPNLLIITLSCISNMIHIL
NESKYQSSTKGQQIDSLKNVARQCMIYAGMIQYRMPRETYSTLINIDVSL
Ligand information
>8tj5 Chain 7 (length=17) Species: 4932 (Saccharomyces cerevisiae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AAAAAAAAAAAAAAAAA
Receptor-Ligand Complex Structure
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PDB8tj5 Implications of a multiscale structure of the yeast nuclear pore complex.
Resolution6.6 Å
Binding residue
(original residue number in PDB)
Y285 P426 T429 L430 S431 I432 W435 Y469 R473
Binding residue
(residue number reindexed from 1)
Y246 P387 T390 L391 S392 I393 W396 Y430 R434
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0017056 structural constituent of nuclear pore
Biological Process
GO:0000055 ribosomal large subunit export from nucleus
GO:0006606 protein import into nucleus
GO:0006913 nucleocytoplasmic transport
GO:0006999 nuclear pore organization
GO:0015031 protein transport
GO:0016973 poly(A)+ mRNA export from nucleus
GO:0051028 mRNA transport
Cellular Component
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005643 nuclear pore
GO:0016020 membrane
GO:0031965 nuclear membrane
GO:0044612 nuclear pore linkers
GO:0044615 nuclear pore nuclear basket

View graph for
Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8tj5, PDBe:8tj5, PDBj:8tj5
PDBsum8tj5
PubMed37738963
UniProtP34077|NIC96_YEAST Nucleoporin NIC96 (Gene Name=NIC96)

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