Structure of PDB 8pj4 Chain R Binding Site BS01

Receptor Information
>8pj4 Chain R (length=198) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GISRDNWHKRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGG
NKKYRALRLDVGNFSWGSECCTRKTRIIDVVYNASNNELVRTKTLVKNCI
VLIDSTPYRQWYESHYALPLGRKEEEILNKKRSKKIQKKYDERKKNAKIS
SLLEEQFQQGKLLACIASRPGQCGRADGYVLEGKELEFYLRKIKARKG
Ligand information
>8pj4 Chain A (length=1754) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucugaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucgcuccuacuuggauaacugug
guaauucuagagcuaauacaugccgacgggcgcugacccccuucgcgggg
gggaugcgugcauuuaucaguggugacucuagauaaccucgggccgaucg
cacgccccccguggcggcgacgacccauucgaacgucugcccuaucaacu
uucgaugguagucgccgugccuaccauggugaccacgggugacggggaau
caggguucgauuccggagagggagccugagaaacggcuaccacauccaag
gaaggcagcaggcgcgcaaauuacccacucccgacccggggagguaguga
cgaaaaauaacaauacaggacucuuucgaggcccuguaauuggaaugagu
ccacuuuaaauccuuuaacgaggauccauuggagggcaagucuggugcca
gcagccgcgguaauuccagcuccaauagcguauauuaaaguugcugcagu
uaaaaagcucguaguuggaucuugggagcgggcgggcgguccgccgcgag
gcgagccaccgcccguccccgccccucucggcggcccgaagcguuuacuu
ugaaaaaauuagaguguucaaagcaggcccgagccgccuggauaccgcag
cuaggaauaauggaauaggaccgcgguucuauuuuguugguuuucggaac
ugaggccaugauuaagagggacggccgggggcauucguauugcgccgcua
gaggugaaauucuuggaccggcgcaagacggaccagagcgaaagcauuug
ccaagaauguuuucauuaaucaagaacgaaagucggagguucgaagacga
ucagauaccgucguaguuccgaccauaaacgaugccgaccggcgaugcgg
cggcguuauucccaugacccgccgggcagcuuccgggaaaccaaagucuu
uggguuccggggggaguaugguugcaaagcugaaacuuaaaggaauugac
ggaagggcaccaccaggaguggagccugcggcuuaauuugacucaacacg
ggaaaccucacccggcccggacacggacaggauugacagauugauagcuc
uuucucgauuccgugggugguggugcauggccguucuuaguugguggagc
gauuugucugguuaauuccgauaacgaacgagacucuggcaugcuaacua
guuacgcgacccccgagcggucggcgucccccaacuucuuagagggacaa
guggcguucagccacccgagauugagcaauaacaggucugugaugcccuu
agauguccggggcugcacgcgcgcuacacugacuggcucagcgugugccu
acccuacgccggcaggcgcggguaacccguugaaccccauucgugauggg
gaucggggauugcaauuauuccccaugaacgaggaauucccaguaagugc
gggucauaagcuugcguugauuaagucccugcccuuuguacacaccgccc
gucgcuacuaccgauuggaugguuuagugaggcccucggaucggccccgc
cgggggcccuggcggagcgcugagaagacggucgaacuugacuaucuaga
ggaaguaaaagucguaacaagguuuccguaggugaaccugcggaaggauc
auua
...<<<<<.[.((((>>>>><<<.<<<<<<...<.<<..<......<<<.
<<<..<<....<<....<<..........>>...>>.>>......<<...
.....<<<.<....<<....<<<<<.............<<.....<<.<<
<.....>>>.>>......>>.........<<<<...<<<<........>>
>>...>>>><<..<<<<<...<......>..>>>>>......>>...<<<
<.<<<<......>>>>>>>>.>>.>>>...>>..>.>>>.<<<....<<<
....<<<<<<<.........>>>>>>>>>>......>>>...<<<.<<<<
....>>>>....>>>.>>.<<.<<<..........>>>.>>.<.<<....
>>.>...>>>>>>.........<<<....<<<<...>>>>..>>>..>..
.>>.>.....<..<...<<..<<....>>..>>.....>...>.....<<
..<...........>..>>.........<<<<<((......<<<<.....
<<..))>>.......>>>>.>>>>>..>>>>>>.>>>.........<.<(
(.....<.<<...<<<.<<.....<..<<<<<<<<<<<<<.<<<<....>
>>>....>>>>>>>>..>>>>>.><<.<.........>.>>...<<<<<<
.<.......<<...<.......>.<<<<.......>>>>...>>......
>.>>>..>>>........<.<<.<<<<<..................>>.>
>>.>>.>....>>....<<<<<<..<...<<<<..<<..<<<<<<<<...
<<<......>>>......>>>>>>>>..>>.......<<....>>...>>
>>..>..>>>.>>>...>>>...>>.>....<<<<<<<...<...<<<<.
<.....>.>>>>...>>>>>>>>..........<<<.<<.<<<..<.<<<
<<<.<<<........>>>>>>>>>.>..>>>...<<..))>>...>>...
..>>>.>.>.<<<......<<<<....>>>>....>>>..)))).]<<<<
<.<<<<<<<..<<..<<<<<..<<<.<<<<<<......<<........>>
..........<<<<<.<....<<<<<<.......<<.<<<........>>
>.>>.....>>>>>>...<<.<<<..<<.<<<<<<....<<<.<<<<<..
..>>>...<<<......>>>...>>.>>>....<<<...<...<<<<..<
<<<<<<<<<<<.......>>>>.>>>>.....>>>>..>>>>..>.....
<<<<<.....>>>>>........>>>....>>>.>>>.....>>>>>>>.
....>.>>>>>...>>.>>>>.>>>.....<<.<<<........<.....
..<<<.<<<<....>>>>.>>>....>.........>>>.>>......<.
....<<<<<..........>>>>>.....>.....>>>>>.....<<<<<
<<<.......>>>>>>>>......>>...>>>>>>>>>>.>>....<..<
<.<..<<<<.<<....<<<<<<<<.<<<..<<<<.<<...<<<<<.....
..................>>>>>...>>.>>>>..>>>.>>>>>>>>...
>>.>>>>...>.>>...>.....<<<<<<<<<<..>>>>>>>>>>.....
....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8pj4 UCSF ChimeraX: Structure visualization for researchers, educators, and developers
Resolution3.2 Å
Binding residue
(original residue number in PDB)
G2 I3 R5 N7 H9 K10 R11 R12 T14 G16 K19 Y21 K23 K24 R25 K26 Y27 L29 G30 R31 P32 A33 A34 R41 R42 I43 H44 T45 R47 V48 R49 G50 N52 K53 K54 Y55 R56 L58 R59 N64 S66 T73 R74 S86 N87 V97 K98 N99 S142 K143 K144 I145 K147 K148 Y149 R152 A176 R178 G180 Q181 C182 G183 R184 D186 G187
Binding residue
(residue number reindexed from 1)
G1 I2 R4 N6 H8 K9 R10 R11 T13 G15 K18 Y20 K22 K23 R24 K25 Y26 L28 G29 R30 P31 A32 A33 R40 R41 I42 H43 T44 R46 V47 R48 G49 N51 K52 K53 Y54 R55 L57 R58 N63 S65 T72 R73 S85 N86 V96 K97 N98 S133 K134 K135 I136 K138 K139 Y140 R143 A167 R169 G171 Q172 C173 G174 R175 D177 G178
External links
PDB RCSB:8pj4, PDBe:8pj4, PDBj:8pj4
PDBsum8pj4
PubMed
UniProtP62241|RS8_HUMAN Small ribosomal subunit protein eS8 (Gene Name=RPS8)

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