Structure of PDB 8cq7 Chain R Binding Site BS01

Receptor Information
>8cq7 Chain R (length=129) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MVDATAPKKRTFKQFSFKGVDLKDLVEMPTEEFTKLCGARVRRRFSRGLD
SKPMGLIKKLRAARAATEPNERPAVVKTHLRNMIVVPEMIGSVVGVYNGK
VFNTVEIKPEMVGHYLGEFSITYTPVRHG
Ligand information
>8cq7 Chain 1 (length=3216) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugaccucaaaucagguaggacuacccgcugaacuuaagcauaucaauaag
cggaggaaaagaaaccaacagggauugccucaguagcggcgagugaagcg
gcaaaagcucaaauuugaaaucuggcgucuuuggcguccgaguuguaauu
ugaagaagguaucuuugggcccggcucuugucuauguuccuuggaacagg
acgucacagagggugagaaucccgugcgaugagaugacccgggucugugu
aaaguuccuucgacgagucgaguuguuugggaaugcagcucuaagugggu
gguaaauuccaucuaaagcuaaauauuggcgagagaccgauagcgaacaa
guacagugauggaaagaugaaaagaacuuugaaaagagagugaaaaagua
cgugaaauuguugaaagggaagggcuugagaucagacuugguauuuugca
ugcgguuuaccgggccagcaucgguuuggagcggcaggauaauggcggag
gaauguggcacggcuucugcuguguguuauagccucugacgauacugcca
gccuagaccgaggacugcgguuuaccuaggauguuggcauaaugaucuua
agucgcccgucuugaaacacggaccaaggagucuaacgucuaugcgagug
uuuggguguaaaacccguacgcguaaugaaagugaacgaaggugggggcc
cauuagggugcaccaucgaccgauccugauguguucggauggauuugagu
aagagcauagcuguugggacccgaaagauggugaacuaugccugaauagg
gugaagccagaggaaacucugguggaggcucguagcgguucugacgugca
aaucgaucgucgaauuuggguauaggggcgaaagacuaaucgaaccaucu
aguagcugguuccugccgaaguuucccucaggauagcagaagcucguauc
aguuuuaugagguaaagcgaaugauuagaagucuugggguugaaaugacc
uuaacuuauucucaaacuuuaaauauguaagaaguccuuguugcuuaauu
gaacguggacaauugaaugaagagcuuuuagugggccauuuuugguaagc
agaacuggcgaugcgggaugaaccgaacgugaaguuaaagugccggaaug
cacgcucaucagacaccacaaaagguguuaguucaucuagacagccggac
gguggccauggaagucggaauccgcuaaggaguguguaacaacucaccgg
ccgaaugaacuagcccugaaaauggauggcgcucaagcgugcuacuuaua
cuucaccgugauugcuguuuugacgcuuucacgaguaggcaggcguggag
gucagugacgaagccuuugcuguaaagcugggucgaacggccucuagugc
agaucuuggugguaguagcaaauauucaaaugagaacuuugaagacugaa
guggggaaagguuccaugucaacagcaguuggacauggguuagucgaucc
uaagagauggggaagcuccguuucaacgugcuugauuuuucaggccaacc
aucgaaagggaauccgguuaaaauuccggaacuuggauauggauucuuca
cggcaacguaacugaauguggagacgucggcgugagcccugggaggaguu
aucuuuucuucuuaacagcuuaucacccuggaauugguuuauccggagau
ggggucuuauggcuggaagagcgcgguaauuuugccgcguccggugcgcu
uacgacgguccuugaaaauccacaggaaggaauaguuuucaugccaaguc
guacucauaaccgcagcaggucuccaagguuaacagccucuaguugauag
aauaauguagauaagggaagucggcaaaauagauccguaacuucgggaua
aggauuggcucuaaggaucgguuuaacgaucaacuuagaacugguacgga
caaggggaaucugacugucuaauuaaaacauagcauugugauggucagaa
agugauguugacacaaugugauuucugcccagugcucugaaugucaaagu
gaagaaauucaaccaagcgcggguaaacggcgggaguaacuaugacucuc
uuaagguagccaaaugccucgucaucuaauuagugacgcgcaugaaugga
uuaacgagauucccacugucccuaucuacuaucuagcgaaaccacagcca
agggaacgggcuuggcagaaucagcggggaaagaagacccuguugagcuu
gacucuaguuugacauugugaaaagacauggaggguguagaauaaguggg
agcuucggcgccggugaaauaccacuaccucuauaguuuuuuuacuuauu
caaugaagcggagcuggaggucaaacuccacguucuagcauuaagcccuc
ugggcgauccggguugaagacauugucagguggggaguuuggcuggggcg
gcacaucuguuaaacgauaacgcagguguccuaagggggacucauggaga
acagaaaucuccaguagaacaaaaggguaaaaguccccuugauuuugauu
uucagugugaauacaaaccaugaaaguguggccuaucgauccuuuagucc
cucggaauuugaggcuagaggugccagaaaaguuaccacagggauaacug
gcuuguggcagucaagcguucauagcgacauugcuuuuugauucuucgau
gucggcucuuccuaucauaccgaagcagaauucgguaagcguuggauugu
ucacccacuaauagggaacgugagcuggguuuagaccgucgugagacagg
uuaguuuuacccuacugaugaauguuaucgcaauaguaauugaacuuagu
acgagaggaaccguucauucagauaauugguuuuugcggcugucugauca
ggcaacgccgcgaagcuaccaucugcuggauuauggcugaacgccucuaa
gucagaauccaugcuagaacgcgaugauuuuugcccugcacauuuuagau
ggauacgaauaagacuuuuuagucgcuggaccauagcaggcuggcaacgg
ugcgcuuagcggaaaggcuuugugcgcuugccggcggauagcaaugucaa
caugcgcggggauaaauccuuugcauacgacuuagauguacaacggagua
uuguaagcaguagaguagccuuguuguuacgaucugcugagauuaagcuc
uuguugucugauuugu
.......................<<<<<<.....<......>......>>
>>>.>.........<<....>>..<<<<<......<.......>.....>
>>>>..[[[...........<<.<<<<<<...>>>>>>.>>.........
....<<<<<...<<<<<<<<<<<<.<<<<<<<<....<<<<......>>>
>.(.......<<<......)>>>..>.>>>>>>>....>>>>>>>>....
>>>>..>>>>>........<<<<<<<........>>>>>>>.....((((
(..<<<<<<)))))..]]]...............................
...<<....>>...............<<<<....>>>>............
......................<<<<<<<<<<<<.....<<<<..<<<<.
.>>>>..>>>>..<<<<<<<.<<<<<<<<.<<<<<<<....<<.<<<<<<
<......<<<<<<......>>>>>>.......>>>>>>.>.>>.>>>>>.
>>>>>>>>>>........<<<..>>>.....>>>>>>>....>>>>>>>>
>>>>..<<<<........>>>><<<<<<....<<<<<<.<<<<<<..<<<
..<<<<<.....>>>>>..>>>...<<....>>.......<<<<<..<<<
<....>>>>...>>>>>.<<<<<<<<...<<....>>...>>>.>>>.>>
....>>>>>>.>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<
<....<<<<<<<....>>>>>>>.....>>>...<<<<.<<.<<......
..>>>>>>>>....>>>>>>>>>...<<.......>>......>>>>>>.
..>..>.>>..<<<<<<....<.<<<....>>>.><<<<<<<<<<...<<
<.<<<<<<<.....<<<....<<<....<<<<...<<<<<.......>>>
>>.>>>>....>>>..>.>>.....>>>>>...<<<<.<<<<.<......
>>>>>.>>>>.....>>>>>.>>>>>>>>.>>..<<<<.<<<<<.....>
>>>>.>>>>....<<<......>>>...<<<<<<<..<<<<(((.....<
<<<<<.....<<..........<<<.<<<<<<<<<<.......<<<<<.<
<<...<<.........>>...>>>.........<<......>>...>>>>
>...>>>>>>>>>>>>>..........))).>>...>>>>>>.>>>>..>
>>>>>><<<<<..<<.........>>..>>>>>....>>>>>>..<<<<<
<<<.<<......<<<<..<<<....>>>.>>>>...>>>>>>>>>>....
....>>>>>><<.....<<.....<<<<<<.......>>>>>><<<<...
..<<<<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<<<<
...<<....<<<....>>>..........<<<<<<....>>>>>>.....
.>>....>>...<<<<<........>>>>>))<<<<.<<<<<<<.....<
<<....>>>.......<<<<<<...<<<<.<<<<<<<.<<<<<<<<<<..
{{{..>>>>>><...<<<<<....<<<<<<....<<<.....>>>....>
>>>>>.....>>>>>....><<<<<<<......>>>>>>>>>>>...>>>
>>>>.>>>>.........>>>>>>..........>>>..>>>>>>>>>>>
>..>>.....<<......>>>>>>>.<<<<.....>>>>..>>>>..<<<
<.....<<<<<<<.<<...............<<<<<..............
.>>>>><<.<<<<<<<<<<<......>>>>>..>>>>>>.>>........
....<<<<<<<<<..<<<.........>>>..<<<<<<<....<<<<...
..>>>>......>>>>>>>...<<..<<<..<<<<<<....<<<.....<
<<<....>>>>.....>>>.>>>>..>>>>><<<<<<.......>>>>>>
........<...........<<<<<.......>>>>>.....>.....>>
....>>.>>>>>>>.....>>.>>>>>>>..>>>>>>....>>....<<<
<<........>>>>>....[[[[[..{{{.{{......[[[[.{{[[[[.
.<<<<<.<<<<<<<<..<<<<<<<<<<...<.<<................
............................>>.>...>>>>>>>>>>...<<
<<<.....<<<<..<<<<<......>>>>>..............<<<<..
.>>>>..>>>>..>>>>>.....>>>>>>>>..>>>>>...<<<.....>
>>..<<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<
.......>>>>>>.....<<...(((>>....>>>>>>>...<<<.<<<<
<.......>>>>.>>>>.<<<....>>>.>>))).......((((((..(
(((.>>>>>>))))))))))..........]]]]..}}]]]].......<
<.<...<<<<<<...<<.......>>...>>>>>>....>.>.>......
.<<<<<.<<<<<<..<.<<<<<<<......>>>>>>>...>.<<<.....
....>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>
>>....}}..}}}.]]]]]....<<<<<<<<..<<<<...<<<<<.....
............>>>>>..<<<<<...<<<<....<<<<<<<<<<}}}.>
>>>>..>>>>>...>>>>..>>>>>.<<<<...<<<<<...........>
>>>>...>>>>.>>>>....>>>>>>>>.....<<<<<<.<<<.<.....
<<..........<<<......>>>......>>.......<<<<<<...<<
<<<<<..<<<......>>>..>>>>>>>.>>>>>>..............>
.>>>.>>>>>>..<<<<<<<.............>>....<<<<<<<<<.<
<<....<<<<.<..<<<<<......>>>>>..>>>>>...>>>....>>>
>.>>>>>..>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8cq7 Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
Resolution3.2 Å
Binding residue
(original residue number in PDB)
A74 V75
Binding residue
(residue number reindexed from 1)
A74 V75
External links
PDB RCSB:8cq7, PDBe:8cq7, PDBj:8cq7
PDBsum8cq7
PubMed
UniProtA0A1D8PK22|RS15_CANAL Small ribosomal subunit protein uS19 (Gene Name=RPS15)

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