Structure of PDB 8ceo Chain R Binding Site BS01

Receptor Information
>8ceo Chain R (length=268) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EVFDGNDIENNETKVYEESLDLDLERSNRQVWLVRLPMFLAEKWRDRNNL
HGQELGKIRINKDGSKITLLLNENDNDSIPHEYDLELTKKVVENEYVFTE
QNLKKYQRDRYIPYVKTIPKKTAIVGTVCHECQVMPSMNDPNYHKIVEQR
RNIVKLNNKERITTLDETVGVTMSHTGMSMRSDNSNFLKVGREKAKSNIK
SIRMPKKEILDYLFKLFDEYDYWSLKGLKERTRQPEAHLKECLDKVATLV
KKGPYAFKYTLRPEYKKL
Ligand information
>8ceo Chain N (length=209) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agcacgctgtgtatataatagctatggaacgttcgattcacctccgatgt
gtgttgtacatacataaaaatatcatagctcttctgcgctgtgttggtcg
tagacagctctagcaccgcttaaacgcacgtacgcgctgtcccccgcgtt
ttaaccgccaaggggattactccctagtctccaggcacgtgtcagatata
tacatcgat
Receptor-Ligand Complex Structure
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PDB8ceo Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		R293 K342
Binding residue
(residue number reindexed from 1)		R203 K252
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0000993 RNA polymerase II complex binding
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0001174 transcriptional start site selection at RNA polymerase II promoter
GO:0006355 regulation of DNA-templated transcription
GO:0006366 transcription by RNA polymerase II
GO:0006367 transcription initiation at RNA polymerase II promoter
GO:0006368 transcription elongation by RNA polymerase II
GO:0051123 RNA polymerase II preinitiation complex assembly
Cellular Component
GO:0005634 nucleus
GO:0005674 transcription factor TFIIF complex

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Biological Process
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Cellular Component
External links
PDB RCSB:8ceo, PDBe:8ceo, PDBj:8ceo
PDBsum8ceo
PubMed37014863
UniProtP41896|T2FB_YEAST Transcription initiation factor IIF subunit beta (Gene Name=TFG2)

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