Structure of PDB 8c99 Chain R Binding Site BS01

Receptor Information
>8c99 Chain R (length=103) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MYAVFQSGGKQHRVSEGQTVRLEKLDIATGETVEFAEVLMIANGEEVKIG
VPFVDGGVIKAEVVAHGRGEKVKIVKFRRRKHYRKQQGHRQWFTDVKITG
ISA
Ligand information
>8c99 Chain A (length=945) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agcguacacgguggaugcccuggcagucagaggcgaugaaggacgugcua
aucugcgauaagcgucgguaaggugauaugaaccguuauaaccggcgauu
uccgaauggggaaacccaguguguuucgacacacuaucauuaacugaauc
cauagguuaaugaggcgaaccgggggaacugaaacaucuaaguaccccga
ggaaaagaaaucaaccgagauucccccaguagcggcgagcgaacggggag
cagcccagagccugaaucaguguguguguuaguggaagcgucuggaaagg
cgcgcgauacagggugacagccccguacacaaaaaugcacaugcugugag
cucgaugaguagggcgggacacgugguauccugucugaauaugggggauc
cuccaaggcuaaauacuccugacugaccgauagugaaccaguaccgugag
ggaaaggcgaaaagaaccccggcgaggggagugaaaaagaaccugaaacc
guguacguacaagcagugggagcacgcuuaggcgugugacugcggucagc
gacuuauauucuguagcaagguuaaccgaauaggggagccgaagggaaac
cgagucuuaacugggcguuaaguugcaggguauagacccgaaacccggug
aucaccgggagauagcugguucuccccgaaagcuauuuagguagcgccuc
gugaauucaucuccgggggagaauguuaucacgggagacacacggcgggu
gcuaacguccgucgugaagagggaaacaacccagaccgccagcuaagguc
ccaaagucaugguuaagggggcuaaaccaugcaccgaagcugcggcagcg
acgcuuaugcguuguuggguaggggagcguucuguaagccugcgaaggug
ugcugugaggcaugcuggagguaucagaagugcgaaugcugacau
.<<<<<<<<<<<....<<<..<<<<<<<<<<<<<......<<<<<<.[..
(((.>>>.....<<<<<<<..<<<)))..].>>>......>>>>>>>...
>>>....<<<....>>><<<<<<<....>>>>>>>.<<<<<<<<<.....
....>>>>>>>>>.>>...<<<<<<.....<<....>>......>>>>>.
>.........<<....>>...<<<<<.....<<.....>>....>>>>>.
..<<<..<<<<......<<<<<<<<<<<<<.<<<...<<<<<......>>
>>>((......<<<.....))>>>...>>>...>>>>>>>>>>>>>...>
>>>........<.<.<<<<.........>>>>.>.>......<<<<<..>
>>>>..>>>......>>.>>>>>>>.>>...............<<....>
>....>>.........<<<<.....>>>>.............>....>>>
>>>>>>>>.......<<<<..<<<<<......>>>>>..>>>>.<<<<<<
....<<<<<<<<<<<<<..<<<...<<.....>>...>>>...<<....>
>...<........>.......>>>>>>>>>>>>>..<<.<..<<<<<<<.
...>>>>>>...>..>.>>..<<<<<<....<<<<<....>>>>>.<<<<
<<<<...<<<<<<<...>>>>.>>>...>>>>>>>.>...<<<<<<<<<.
.......>>>>>>>>>....<<<......>>>...<<<<.<<<...<<<(
((.....<<<<<<....))).....>>>>>>.>>>...>>>>>>><<<<<
<<<<....>>>>>>>>>....>>>>>><<<<<<<...<<<......<<<<
<<<<....>>>>>>>>...>>>..>>>>>.>>.....>>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8c99 Cryo-EM captures early ribosome assembly in action.
Resolution3.29 Å
Binding residue
(original residue number in PDB)		G8 K10 E23 K24 K76 R79 K81 H82 R84 K85 Q86 Q87 G88 H89 R90 Q91
Binding residue
(residue number reindexed from 1)		G8 K10 E23 K24 K76 R79 K81 H82 R84 K85 Q86 Q87 G88 H89 R90 Q91
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8c99, PDBe:8c99, PDBj:8c99
PDBsum8c99
PubMed36797249
UniProtP0AG48|RL21_ECOLI Large ribosomal subunit protein bL21 (Gene Name=rplU)

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