Structure of PDB 7zs9 Chain R Binding Site BS01

Receptor Information
>7zs9 Chain R (length=268) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EVFDGNDIENNETKVYEESLDLDLERSNRQVWLVRLPMFLAEKWRDRNNL
HGQELGKIRINKDGSKITLLLNENDNDSIPHEYDLELTKKVVENEYVFTE
QNLKKYQRDRYIPYVKTIPKKTAIVGTVCHECQVMPSMNDPNYHKIVEQR
RNIVKLNNKERITTLDETVGVTMSHTGMSMRSDNSNFLKVGREKAKSNIK
SIRMPKKEILDYLFKLFDEYDYWSLKGLKERTRQPEAHLKECLDKVATLV
KKGPYAFKYTLRPEYKKL
Ligand information
>7zs9 Chain N (length=209) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agcacgctgtgtatataatagctatggaacgttcgattcacctccgatgt
gtgttgtacatacataaaaatatcatagctcttctgcgctgtgttggtcg
tagacagctctagcaccgcttaaacgcacgtacgcgctgtcccccgcgtt
ttaaccgccaaggggattactccctagtctccaggcacgtgtcagatata
tacatcgat
Receptor-Ligand Complex Structure
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PDB7zs9 Structures of transcription preinitiation complex engaged with the +1 nucleosome.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		I289 K290 S291 I292 R293 P325 K341 K342 F347
Binding residue
(residue number reindexed from 1)		I199 K200 S201 I202 R203 P235 K251 K252 F257
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0000993 RNA polymerase II complex binding
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0001174 transcriptional start site selection at RNA polymerase II promoter
GO:0006355 regulation of DNA-templated transcription
GO:0006366 transcription by RNA polymerase II
GO:0006367 transcription initiation at RNA polymerase II promoter
GO:0006368 transcription elongation by RNA polymerase II
GO:0051123 RNA polymerase II preinitiation complex assembly
Cellular Component
GO:0005634 nucleus
GO:0005674 transcription factor TFIIF complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7zs9, PDBe:7zs9, PDBj:7zs9
PDBsum7zs9
PubMed36411341
UniProtP41896|T2FB_YEAST Transcription initiation factor IIF subunit beta (Gene Name=TFG2)

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