Structure of PDB 7w0o Chain R Binding Site BS01

Receptor Information
>7w0o Chain R (length=293) Species: 562,9606 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSGALIPAIYMLVFLLGTTGNGLVLWTVFRSSREKRRSADIFIASLAVAD
LTFVVTLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFCLTGLSF
DRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAMPVMVLRTTGDLEN
TTKVQCYMDYSMVATVSSEWAWEVGLGVSSTTVGFVVPFTIMLTCYFFIA
QTIAGHFRKERIEGLRKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGS
LLHWPCDFDLFLMNIFPYCTCISYVNSCLNPFLYAFFDPRFRQ
Ligand information
Receptor-Ligand Complex Structure
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PDB7w0o Structural insight into apelin receptor-G protein stoichiometry.
Resolution3.78 Å
Binding residue
(original residue number in PDB)		W85 Y88 I109 F110 R168 C181 Y182 M183 Y264
Binding residue
(residue number reindexed from 1)		W60 Y63 I84 F85 R143 C156 Y157 M158 Y239
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0005506 iron ion binding
GO:0009055 electron transfer activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0022900 electron transport chain
Cellular Component
GO:0016020 membrane
GO:0042597 periplasmic space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7w0o, PDBe:7w0o, PDBj:7w0o
PDBsum7w0o
PubMed35817871
UniProtP0ABE7|C562_ECOLX Soluble cytochrome b562 (Gene Name=cybC);
P35414|APJ_HUMAN Apelin receptor (Gene Name=APLNR)

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