Structure of PDB 7w0n Chain R Binding Site BS01
Receptor Information
>7w0n Chain R (length=298) Species:
562,9606
[
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
WKSSGALIPAIYMLVFLLGTTGNGLVLWTVFRSSREKRRSADIFIASLAV
ADLTFVVTLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFCLTGL
SFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAMPVMVLRTTGDL
ENTTKVQCYMDYSMVATVSSEWAWEVGLGVSSTTVGFVVPFTIMLTCYFF
IAQTIAGHFRKERIEGLRKRRRLLSIIVVLVVTFALCWMPYHLVKTLYML
GSLLHWPCDFDLFLMNIFPYCTCISYVNSCLNPFLYAFFDPRFRQACT
Ligand information
>7w0n Chain D (length=15) Species:
9606
(Homo sapiens) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
LQRRCMPLHSRVPFP
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
7w0n
Structural insight into apelin receptor-G protein stoichiometry.
Resolution
4.21 Å
Binding residue
(original residue number in PDB)
W24 I31 Y35 W85 T89 Y93 I109 F110 R168 Y182
Binding residue
(residue number reindexed from 1)
W1 I8 Y12 W62 T66 Y70 I86 F87 R145 Y159
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0004930
G protein-coupled receptor activity
GO:0005506
iron ion binding
GO:0009055
electron transfer activity
GO:0020037
heme binding
GO:0046872
metal ion binding
Biological Process
GO:0007186
G protein-coupled receptor signaling pathway
GO:0022900
electron transport chain
Cellular Component
GO:0016020
membrane
GO:0042597
periplasmic space
View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB
RCSB:7w0n
,
PDBe:7w0n
,
PDBj:7w0n
PDBsum
7w0n
PubMed
35817871
UniProt
P0ABE7
|C562_ECOLX Soluble cytochrome b562 (Gene Name=cybC);
P35414
|APJ_HUMAN Apelin receptor (Gene Name=APLNR)
[
Back to BioLiP
]