Structure of PDB 7r72 Chain R Binding Site BS01

Receptor Information
>7r72 Chain R (length=134) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIV
KKAVTVHSKRLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESK
GNAFKHKRALVEHIIQAKADAQREKALNEEAEAR
Ligand information
>7r72 Chain 1 (length=641) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
augccugaauagggugaagccagaggaaacucugguggaggcucgcgaau
uuggguauaguagcaaauauucaaaugagaacuuugaagacugaaguggg
gaaagguuccacgucaacagcaguuggacguggguuagucgauccuaaga
gaugguuucaaaggccugauucaggccaccaucgaaagggaauccgguua
agauuccggaaccuggauauggauucuucacgguaacguaacugaaugug
gagacgucggcgcgagcccugggaggaguuaucuuuucuucuuaacagcu
uaucaccccggaauugguuuauccggagauggggucuuauggcuggaaga
ggccagcaccuuugcuggcuccggugcgcuugugacggcccgugaaaauc
cacaggaaggaauaguuuucaugccaggucguacugucuccaaggugaac
agccucuaguugauagaauccguaacuucgggauaaggauuggcucuaag
ggucggguagugagggccuuggucacggccuuggcuugcuacaauuaacg
aucaacuuagaacugguacggacaauaucuagcgaggcugucugaucagg
cauugcguaagcaguagaguagccguuacgaucugcugaga
<<<<<<<<...<<<....<<<<<<<....>>>>>>>.....>>>......
>>>>>>>>....<<.....<<<<<<.......>>>>>><<<<.....<<<
<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<<<<...<<
............<<<<<<...>>>>>>....>>....>>...<<<<<...
.....>>>>>))<<<<.<<<<<<......<<<....>>>.......<<<<
<<...<<<<.<<<<<<<.<<<<<<<<<<..(((..>>>>>><...<<<<<
....<<<<<<....<<<.....>>>....>>>>>>.....>>>>>....>
<<<<<<<......>>>>>>>>>>>...>>>>>>>.>>>>.........>>
>>>>............>>.>>>>>>>>>>>>..>>.>>>>>.<<<<....
.>>>>..>>>>..<<<<.<<<<<<.<<<<.....................
<<<<<.<<<<<<<<..<<..<<<<..>>>>..>>>>>>>>>>......>>
>>>......>>>...>>>>>>>.....>>>>>>...<<<<<<<))).>>>
>>..>>....<<<<....<<.......>>...>>>>.....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7r72 Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Resolution3.07 Å
Binding residue
(original residue number in PDB)
A2 N3 R5 T6 K8 R9 L10 V17 K19 R20 K21 W23 L24 P26 S37 R38 N39 R42 K43 K46 K53 V57 H58 R88 L89 P90 Q92 W95 I96 R100 V101 R103 R104 K108 Y109 R110 H118 Y120 H121 Y124 K125 K128 G129 H134 K135 R136
Binding residue
(residue number reindexed from 1)
A1 N2 R4 T5 K7 R8 L9 V16 K18 R19 K20 W22 L23 P25 S36 R37 N38 R41 K42 K45 K52 V56 H57 R60 L61 P62 Q64 W67 I68 R72 V73 R75 R76 K80 Y81 R82 H90 Y92 H93 Y96 K97 K100 G101 H106 K107 R108
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:7r72, PDBe:7r72, PDBj:7r72
PDBsum7r72
PubMed36482249
UniProtP0CX82|RL19A_YEAST Large ribosomal subunit protein eL19A (Gene Name=RPL19A)

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