Structure of PDB 7of2 Chain R Binding Site BS01

Receptor Information
>7of2 Chain R (length=140) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LRNRVTDRYFRIQEVLKHARHFRGRKNRCYRLAVRTVIRAFVKCTKARYL
KKKNMRTLWINRITAASQEHGLKYPALIGNLVKCQVELNRKVLADLAIYE
PKTFKSLAALASRRRHEGFAAALGDGKEPEGIFSRVVQYH
Ligand information
>7of2 Chain A (length=1410) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaaccccaccuuacuaccagacaaccuuagccaaa
ccauuuacauaaaguauaggcgauagaaauugauggcgcaauagauauag
uaccgcaagggaaagaugaaaaaccaagcauaauauagcaaggacuaacc
ccuauaccuucugcauaaugaauuaacuagaaauaacuuugcaaggagag
ccaaagcuaagacccccgaaaccagacgagcuaccuaagaacagcuaaaa
gagcacacccgucuauguagcaaaauagugggaagauuuauagguagagg
cgacaaaccuaccgagccuggugauagcugguuguccaagauagaaucuu
aguucaacuuuaaauuugcccacagaacccucuaaauccccuuguaaauu
uaacuguuaguccaaagaggaacagcucuuuggacacuaggaaaaaaccu
uguagagagaguaaaaaauuuaacacccauaguaggccuaaaagcagcca
ccaauuaagaaagcguucaagcucaacacaaaaaucccaaacauauaacu
gaacuccucacacccaauuggaccaaucuaucacccuauagaagaacuaa
uguuaguauaaguaacaugaaaacauucuccuccgcauaagccugcguca
gauacugacaauuaacagcccaauaucuacaaucaaccaacaagucauua
uuacccucacugucaacccaacacaggcaugcucauaaggaaagguuaaa
aaaaguaaaaggaacucggcaaaucuuaccccgccuguuuaccaaaaaca
ucaccucuagcaucaccaguauuagaggcaccgccucacuuguuccuuaa
auagggaccuguauggcuccacgaggguucagcugucucuuacuuuuaac
cagugaaauugaccugcccgugaagaggcgggcauaacacagcaagacga
gaagacccuauggagcuuuaauuuauuaaugcaaacaccugcauuaaaaa
uuucgguuggggcgaccucggagcagaacccaaccuccgagcaguacaug
cuaagacuucaccagucaaagcgaaccucaauugauccaauaacuugacc
aacggaacaaguuacccuagggauaacagcgcaauccuauucuagagucc
auaucaacaauaggguuuacgaccucgauguuggaucaggacaucccgau
ggugcagccgcuauuaaagguucguuuguucaacgauuaaaguccuacgu
gaucugaguucagaccggaguaauccaggucgguuucuaucuacuuuaau
uccucccuguacgaaaggacaagagaaauaaggccuacuucacaaagcgc
cuucccccguaaaugauaucaucucaacuuaguauuauacccacacccaa
gaacaggguu
<<<.......<<<<.................................<..
....>...........<<.....>>.........>>.>>...........
..<<....>>................>>>...........<<<.......
>>>...<.<........>.>.<<<<<<.........<<<.<<..<<....
>>...>>.>>>...<<.<...<<<<.<.....<<<<<.<<<..<<<....
.>>>...<<<<.<<<<........>>>>>>>>....>>>.>>>>>...<<
.......>>......>.>>>>......>.>>..<<<<<<....<<<<...
.>>>><<<.<<<<<<<<<<.....<<..........>>.....>>>>>>>
>>>..>>>.<<<<<<<<<<......>>>>>>>>>>.<.<<<......>>>
.>..<<<.<<<...<..............<....<<<.........>>>.
...>.......<<<......>>>..........................>
...>>>>>>........>>>>>>...<<<<<......>>>>>........
.>>>>>><......<<..<<<....>>><<<<..<<<<........<<<<
<...>>>>>......<<<...<<<<.......................>>
>>.......>>>.....<<......>>.>>>>.....>>>>..<<<<...
<<<<<<<<.<<................<<<<<<..<<<.........>>>
...<<<<<<.............>>>>>>....<<<..<<..<<<<<<...
..>>>>>>..>>..>>>....>>.>>>>........>>.>>>>>>>>>>>
>.>>.....>.....<<<<<........>>>>>.......<<..<<<.<<
......<<<<.<<<<<<..<<<<<.<<<<<<<<......>>>>>>>>>>>
>>..<<<<.....>>>><<<<<<...........>>>>>>..<<.....<
<<..<<<<.....>>>>..>>>....>>.........<<<....>>>...
.........>>>>..>>>>>>.......<<<....<<<<<<...<<....
...>>...>>>>>>.....>>.>.......<<<<<..<<<<<..<<.<<<
<<<......>>>>>>...>>.<<<<<.....>>>>>.....>>>>>....
..>>>>.>....<<<<<<<....>>>.>>>>....>>..>>>.>>...<<
<.<<<.................>>>.>>><<<<<...<<<....>>>.>>
>>>......<<<................>>>.............<<<<..
.....>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7of2 Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		L10 R11 N12 R13 V14 D16 R17 R20 H30 F31 R32 R34 K35 R37 C38 Y39 R40 L41 V43 R44 R48 A49 K52 C53 A56 R57 Y58 K60 K61 K62 M64 R65 W68 I69 Y83 P84 N98 R99 R124 F128
Binding residue
(residue number reindexed from 1)		L1 R2 N3 R4 V5 D7 R8 R11 H21 F22 R23 R25 K26 R28 C29 Y30 R31 L32 V34 R35 R39 A40 K43 C44 A47 R48 Y49 K51 K52 K53 M55 R56 W59 I60 Y74 P75 N89 R90 R115 F119
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005761 mitochondrial ribosome
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7of2, PDBe:7of2, PDBj:7of2
PDBsum7of2
PubMed34135319
UniProtQ9BYC9|RM20_HUMAN Large ribosomal subunit protein bL20m (Gene Name=MRPL20)

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