Structure of PDB 6zm6 Chain R Binding Site BS01

Receptor Information
>6zm6 Chain R (length=140) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LRNRVTDRYFRIQEVLKHARHFRGRKNRCYRLAVRTVIRAFVKCTKARYL
KKKNMRTLWINRITAASQEHGLKYPALIGNLVKCQVELNRKVLADLAIYE
PKTFKSLAALASRRRHEGFAAALGDGKEPEGIFSRVVQYH
Ligand information
>6zm6 Chain A (length=1531) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccagacaaccuuagc
caaaccauuuacccaaauaaaguauaggcgauagaaauugaaaccuggcg
caauagauauaguaccgcaagggaaagaugaaaaauuauaaccaagcaua
auauagcaaggacuaaccccuauaccuucugcauaaugaauuaacuagaa
auaacuuugcaaggagagccaaagcuaagacccccgaaaccagacgagcu
accuaagaacagcuaaaagagcacacccgucuauguagcaaaauaguggg
aagauuuauagguagaggcgacaaaccuaccgagccuggugauagcuggu
uguccaagauagaaucuuaguucaacuuuaaauuugcccacagaacccuc
uaaauccccuuguaaauuuaacuguuaguccaaagaggaacagcucuuug
gacacuaggaaaaaaccuuguagagagaguaaaaaauuuaacacccauag
uaggccuaaaagcagccaccaauuaagaaagcguucaagcucaacaccca
cuaccuaaaaaaucccaaacauauaacugaacuccucacacccaauugga
ccaaucuaucacccuauagaagaacuaauguuaguauaaguaacaugaaa
acauucuccuccgcauaagccugcgucagauuaaaaugaacugacaauua
acagcccaauaucuacaaucaaccaacaagucauuauuacccucacuguc
aacccaacacaggcaugcucauaaggaaagguuaaaaaaaguaaaaggaa
cucggcaaaucuuaccccgccuguuuaccaaaaacaucaccucuagcauc
accaguauuagaggcaccgccugcccagugacacauguuuaacggccgcg
guacccuaaccgugcaaagguagcauaaucacuuguuccuuaaauaggga
ccuguaugaauggcuccacgaggguucagcugucucuuacuuuuaaccag
ugaaauugaccugcccgugaagaggcgggcauaacacagcaagacgagaa
gacccuauggagcuuuaauuuauuaaugcaaacaguaccaaaccugcauu
aaaaauuucgguuggggcgaccucggagcagaacccaaccuccgagcagu
acaugcuaagacuucaccagucaaagcgaacuacuauacucaauugaucc
aauaacuugaccaacggaacaaguuacccuagggauaacagcgcaauccu
auucuagaguccauaucaacaauaggguuuacgaccucgauguuggauca
ggacaucccgauggugcagccgcuauuaaagguucguuuguucaacgauu
aaaguccuacgugaucugaguucagaccggaguaauccaggucgguuucu
aucuacuuucaaauuccucccuguacgaaaggacaagagaaauaaggccu
acuucacaaagcgccuucccccguaaaugauaucaucucaacuuaguauu
auacccacacccacccaagaacaggguuugu
<<<.......<<<<....................................
.<......>.........<.....<<.....>>....>........>>.>
>.............<<....>>......................>>>...
........<<<.......>>>...<.<........>.>.<<<<<<.....
....<<<.<<..<<....>>...>>.>>>...<<.<...<<<<.<.....
<<<<<.<<<..<<<.....>>>...<<<..<<<<........>>>>.>>>
....>>>.>>>>>...<<.......>>......>.>>>>......>.>>.
.<<<<<<....<<<<....>>>><<<.<<<<<<<<<<.....<<......
....>>.....>>>>>>>>>>..>>>.<<<<<<<<<<......>>>>>>>
>>>.<.<<<......>>>.>..<<<.<<<...<..............<..
..<<<.........>>>....>.......<<<......>>>.........
...........................>...>>>>>>........>>>>>
>...<<<<<......>>>>>.........>>>>>><......<<..<<<.
...>>><<<<..<<<<........<<<<<.<<.....>>.>>>>>.....
.<<<...<<<<.......................>>>>.......>>>..
...<<......>>.>>>>.....>>>>..<<<<...<<<<<<<<.<<...
......<......<<<<<<..<<<.........>>>...<<<<<<.....
........>>>>>>....<<<.<<<..<<<<<....>>>..>>>>><<<<
<<......>>>>>>........<...........<<<<<<.....>>>>>
>.....>....>>>....>>.>>>>.....>..>>.>>>>>>>>>>>>.>
>.....>.....<<<<<........>>>>>.......<<..<<<.<<...
...<<<<.<<<<<<..<<<<<.<<<<<<<<....<..>......>>>>>>
>>>>>>>..<<<<.....>>>><<<<<<...........>>>>>>..<<.
....<<<..<<<<.....>>>>..>>>...........>>.........<
<<....>>>............>>>>..>>>>>>.......<<<..<.<<<
<<<...<<.......>>...>>>>>>...>.>>.>.......<<<<<.<<
<<<<..<<.<<<<<<......>>>>>>...>>.<<<<<.....>>>>>..
...>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>....>>.
.>>>.>>...<.<<<.<<<.................>>>.>>><<<<<..
.<<<....>>>.>>>>>......<<<................>>>.....
.>..........<<<<.......>>>>....
Receptor-Ligand Complex Structure
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PDB6zm6 Mechanism of membrane-tethered mitochondrial protein synthesis.
Resolution2.59 Å
Binding residue
(original residue number in PDB)		L10 R11 N12 R13 V14 T15 R17 R20 H30 F31 R32 R34 K35 R37 Y39 R40 L41 V43 R44 R48 A49 K52 C53 A56 R57 Y58 K60 K61 M64 R65 W68 Y83 P84 N98 R99 K100 R124 F128
Binding residue
(residue number reindexed from 1)		L1 R2 N3 R4 V5 T6 R8 R11 H21 F22 R23 R25 K26 R28 Y30 R31 L32 V34 R35 R39 A40 K43 C44 A47 R48 Y49 K51 K52 M55 R56 W59 Y74 P75 N89 R90 K91 R115 F119
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005761 mitochondrial ribosome
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6zm6, PDBe:6zm6, PDBj:6zm6
PDBsum6zm6
PubMed33602856
UniProtQ9BYC9|RM20_HUMAN Large ribosomal subunit protein bL20m (Gene Name=MRPL20)

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