Structure of PDB 6up7 Chain R Binding Site BS01

Receptor Information
>6up7 Chain R (length=322) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQS
TVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRD
ACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALL
AVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPM
VVISVLNTIIANKLTVMVRQAAEQFSMAIEPGRVQALRHGVRVLRAVVIA
FVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINP
ILYNLVSANFRHIFLATLACLC
Ligand information
Receptor-Ligand Complex Structure
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PDB6up7 Structure of the neurotensin receptor 1 in complex with beta-arrestin 1.
Resolution4.2 Å
Binding residue
(original residue number in PDB)		L54 F127 Y145 T225 F326 Y342
Binding residue
(residue number reindexed from 1)		L5 F78 Y96 T176 F265 Y281
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0016492 G protein-coupled neurotensin receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6up7, PDBe:6up7, PDBj:6up7
PDBsum6up7
PubMed31945771
UniProtP30989|NTR1_HUMAN Neurotensin receptor type 1 (Gene Name=NTSR1)

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