Structure of PDB 6j2x Chain R Binding Site BS01

Receptor Information
>6j2x Chain R (length=400) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NYEVSEKAFLLTQSKVSIEQRKEAAEFVLAKIKEEEMAPYYKYLCEEYLV
NNGQSDLEHDEKSDSLNEWIKFDQELYNELCKKNESKIKELNEKIQKLEE
DDEGELEQAQAWINLGEYYAQIGDKDNAEKTLGKSLSKAISTGAKIDVML
TIARLGFFYNDQLYVKEKLEAVNSMIEKGGDWERRNRYKTYYGIHCLAVR
NFKEAAKLLVDSLATFTSIELTSYESIATYASVTGLFTLERTDLKSKVID
SPELLSLISTTAALQSISSLTISLYASDYASYFPYLLETYANVLIPCKYL
NRHADFFVREMRRKVYAQLLESYKTLSLKSMASAFGVSVAFLDNDLGKFI
PNKQLNCVIDRVNGIVETNRPDNKNAQYHLLVKQGDGLLTKLQKYGAAVR
Ligand information
>6j2x Chain Y (length=27) Species: 559292 (Saccharomyces cerevisiae S288C) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ENWDDVEVDDDFTNELKAELDRYKREN
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6j2x Structural Snapshots of 26S Proteasome Reveal Tetraubiquitin-Induced Conformations.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		F305 F328 R334 S360 F363 D367 N374
Binding residue
(residue number reindexed from 1)		F283 F306 R312 S338 F341 D345 N352
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
GO:0005515 protein binding
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
Cellular Component
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005838 proteasome regulatory particle
GO:0008541 proteasome regulatory particle, lid subcomplex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6j2x, PDBe:6j2x, PDBj:6j2x
PDBsum6j2x
PubMed30792173
UniProtQ06103|RPN7_YEAST 26S proteasome regulatory subunit RPN7 (Gene Name=RPN7)

[Back to BioLiP]