Structure of PDB 6j2c Chain R Binding Site BS01

Receptor Information
>6j2c Chain R (length=400) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NYEVSEKAFLLTQSKVSIEQRKEAAEFVLAKIKEEEMAPYYKYLCEEYLV
NNGQSDLEHDEKSDSLNEWIKFDQELYNELCKKNESKIKELNEKIQKLEE
DDEGELEQAQAWINLGEYYAQIGDKDNAEKTLGKSLSKAISTGAKIDVML
TIARLGFFYNDQLYVKEKLEAVNSMIEKGGDWERRNRYKTYYGIHCLAVR
NFKEAAKLLVDSLATFTSIELTSYESIATYASVTGLFTLERTDLKSKVID
SPELLSLISTTAALQSISSLTISLYASDYASYFPYLLETYANVLIPCKYL
NRHADFFVREMRRKVYAQLLESYKTLSLKSMASAFGVSVAFLDNDLGKFI
PNKQLNCVIDRVNGIVETNRPDNKNAQYHLLVKQGDGLLTKLQKYGAAVR
Ligand information
>6j2c Chain Y (length=27) Species: 559292 (Saccharomyces cerevisiae S288C) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ENWDDVEVDDDFTNELKAELDRYKREN
Receptor-Ligand Complex Structure
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PDB6j2c Structural Snapshots of 26S Proteasome Reveal Tetraubiquitin-Induced Conformations.
Resolution7.0 Å
Binding residue
(original residue number in PDB)		A302 F305 P306 L309 F328 R331 R334 S355 G358 V359 F363 N366 D367 K370 N374
Binding residue
(residue number reindexed from 1)		A280 F283 P284 L287 F306 R309 R312 S333 G336 V337 F341 N344 D345 K348 N352
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
GO:0005515 protein binding
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
Cellular Component
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005838 proteasome regulatory particle
GO:0008541 proteasome regulatory particle, lid subcomplex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6j2c, PDBe:6j2c, PDBj:6j2c
PDBsum6j2c
PubMed30792173
UniProtQ06103|RPN7_YEAST 26S proteasome regulatory subunit RPN7 (Gene Name=RPN7)

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