Structure of PDB 6cnc Chain R Binding Site BS01

Receptor Information
>6cnc Chain R (length=522) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MPVCKNCHGTEFERDLSNANNDLVCKACGVVSEDNPIVSEVALESREATL
NNARRKLRAVSYALHIPEYITDAAFQWYKLALANNFVQGRRSQNVIASCL
YVACRKEKTHHMLIDFSSRLQVSVYSIGATFLKMVKKLHITELPLADPSL
FIQHFAEKLDLADKKIKVVKDAVKLAQRMSKDWMFEGRRPAGIAGACILL
ACRMNNLRRTHTEIVAVSHVAEETLQQRLNEFKNTKAAKLSVQKFRENDV
EDGEARPPSFVKNRKKESGIVPTLQNIVATVTLGCRLDLKTVALHARNAE
YNPKRFAAVIMRIREPKTTALIFASGKMVVTGAKSEDDSKLASRKYARII
QKIGFAAKFTDFKIQNIVGSCDVKFPIRLEGLAFSHGTFSSYEPELFPGL
IYRMVKPKIVLLIFVSGKIVLTGAKQREEIYQAFEAIYPVLSEFRKMSGS
PRNLHLLPTTDTYLSKVSDDPDNLEDVDDEELNAHLLNEEASKLKERIWI
GLNADFLLEQESKRLKQEADIA
Ligand information
>6cnc Chain X (length=51) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ttttcaacatatattagtaatactttttctgaagataaaatgactccatg
g
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6cnc Structural visualization of RNA polymerase III transcription machineries.
Resolution4.1 Å
Binding residue
(original residue number in PDB)		S75 R76 Q118 G119 R121 S122 Y155 L162 F442 S444 K446 V448 Q484 N485 F516 V529
Binding residue
(residue number reindexed from 1)		S45 R46 Q88 G89 R91 S92 Y125 L132 F323 S325 K327 V329 Q365 N366 F397 V410
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0017025 TBP-class protein binding
Biological Process
GO:0006352 DNA-templated transcription initiation

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Molecular Function
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Biological Process
External links
PDB RCSB:6cnc, PDBe:6cnc, PDBj:6cnc
PDBsum6cnc
PubMed30083386
UniProtP13393|TBP_YEAST TATA-box-binding protein (Gene Name=SPT15);
P29056|TF3B_YEAST Transcription factor IIIB 70 kDa subunit (Gene Name=BRF1)

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