Structure of PDB 5e6i Chain R Binding Site BS01

Receptor Information
>5e6i Chain R (length=251) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFFTSVSRPGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWI
EQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCD
VGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHV
AEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDLRCWAL
SFYPAEITLTWDTELVETRPAGDGTFQKWAAVVRYTCHVQHEGLPKPLTL
R
Ligand information
>5e6i Chain T (length=9) Species: 947055 (Influenza A virus (A/Boston/2747243M/2009(H1N1))) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GILGFVFTL
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5e6i Crystal structure of TCR PF8 in complex with flu MP(58-66) epitope presented by HLA-A2
Resolution4.0 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 H70 T73 D77 L81 R97 Y99 Y116 K146 L156 Y159
Binding residue
(residue number reindexed from 1)
Y7 E61 K64 H68 T71 D75 L79 R95 Y97 Y114 K144 L154 Y157
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5e6i, PDBe:5e6i, PDBj:5e6i
PDBsum5e6i
PubMed
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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