Structure of PDB 4cr4 Chain R Binding Site BS01

Receptor Information
>4cr4 Chain R (length=400) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NYEVSEKAFLLTQSKVSIEQRKEAAEFVLAKIKEEEMAPYYKYLCEEYLV
NNGQSDLEHDEKSDSLNEWIKFDQELYNELCKKNESKIKELNEKIQKLEE
DDEGELEQAQAWINLGEYYAQIGDKDNAEKTLGKSLSKAISTGAKIDVML
TIARLGFFYNDQLYVKEKLEAVNSMIEKGGDWERRNRYKTYYGIHCLAVR
NFKEAAKLLVDSLATFTSIELTSYESIATYASVTGLFTLERTDLKSKVID
SPELLSLISTTAALQSISSLTISLYASDYASYFPYLLETYANVLIPCKYL
NRHADFFVREMRRKVYAQLLESYKTLSLKSMASAFGVSVAFLDNDLGKFI
PNKQLNCVIDRVNGIVETNRPDNKNAQYHLLVKQGDGLLTKLQKYGAAVR
Ligand information
>4cr4 Chain Y (length=19) Species: 4932 (Saccharomyces cerevisiae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
DDFTNELKAELDRYKRENQ
Receptor-Ligand Complex Structure
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PDB4cr4 Deep Classification of a Large Cryo-Em Dataset Defines the Conformational Landscape of the 26S Proteasome.
Resolution8.8 Å
Binding residue
(original residue number in PDB)		L309 Y312 D327 S360 F363
Binding residue
(residue number reindexed from 1)		L287 Y290 D305 S338 F341
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
GO:0005515 protein binding
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
Cellular Component
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005838 proteasome regulatory particle
GO:0008541 proteasome regulatory particle, lid subcomplex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4cr4, PDBe:4cr4, PDBj:4cr4
PDBsum4cr4
PubMed24706844
UniProtQ06103|RPN7_YEAST 26S proteasome regulatory subunit RPN7 (Gene Name=RPN7)

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