Structure of PDB 4cr3 Chain R Binding Site BS01

Receptor Information
>4cr3 Chain R (length=400) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NYEVSEKAFLLTQSKVSIEQRKEAAEFVLAKIKEEEMAPYYKYLCEEYLV
NNGQSDLEHDEKSDSLNEWIKFDQELYNELCKKNESKIKELNEKIQKLEE
DDEGELEQAQAWINLGEYYAQIGDKDNAEKTLGKSLSKAISTGAKIDVML
TIARLGFFYNDQLYVKEKLEAVNSMIEKGGDWERRNRYKTYYGIHCLAVR
NFKEAAKLLVDSLATFTSIELTSYESIATYASVTGLFTLERTDLKSKVID
SPELLSLISTTAALQSISSLTISLYASDYASYFPYLLETYANVLIPCKYL
NRHADFFVREMRRKVYAQLLESYKTLSLKSMASAFGVSVAFLDNDLGKFI
PNKQLNCVIDRVNGIVETNRPDNKNAQYHLLVKQGDGLLTKLQKYGAAVR
Ligand information
>4cr3 Chain Y (length=19) Species: 4932 (Saccharomyces cerevisiae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
DDFTNELKAELDRYKRENQ
Receptor-Ligand Complex Structure
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PDB4cr3 Deep Classification of a Large Cryo-Em Dataset Defines the Conformational Landscape of the 26S Proteasome.
Resolution9.3 Å
Binding residue
(original residue number in PDB)		F305 Y312 D327 V330 G358 S360
Binding residue
(residue number reindexed from 1)		F283 Y290 D305 V308 G336 S338
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
GO:0005515 protein binding
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
Cellular Component
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005838 proteasome regulatory particle
GO:0008541 proteasome regulatory particle, lid subcomplex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4cr3, PDBe:4cr3, PDBj:4cr3
PDBsum4cr3
PubMed24706844
UniProtQ06103|RPN7_YEAST 26S proteasome regulatory subunit RPN7 (Gene Name=RPN7)

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