Structure of PDB 4p70 Chain QK Binding Site BS01

Receptor Information
>4p70 Chain QK (length=119) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYA
AQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVD
DTPVPHNGCRPKKKFRKAS
Ligand information
>4p70 Chain QA (length=1500) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uggagaguuugauccuggcucagggugaacgcuggcggcgugccuaagac
augcaagucgugcgggccgcggggucuccguggucagcggcggacgggug
aguaacgcgugggugaccuacccggaagagggggacaacccggggaaacu
cgggcuaaucccccauguggacccgccccuugggguguguccaaagggcu
uugcccgcuuccggaugggcccgcgucccaucagcuaguuggugggguaa
uggcccaccaaggcgacgacggguagccggucugagaggauggccggcca
caggggcacugagacacgggccccacuccuacgggaggcagcaguuagga
aucuuccgcaaugggcgcaagccugacggagcgacgccgcuuggaggaag
aagcccuucgggguguaaacuccugaacccgggacgaaacccccgacgag
gggacugacgguaccgggguaauagcgccggccaacuccgugccagcagc
cgcgguaauacggagggcgcgagcguuacccggauucacugggcguaaag
ggcguguaggcggccuggggcgucccaugugaaagaccacggcucaaccg
ugggggagcgugggauacgcucaggcuagacggugggagaggguggugga
auucccggaguagcggugaaaugcgcagauaccgggaggaacgccgaugg
cgaaggcagccaccugguccacccgugacgcugaggcgcgaaagcguggg
gagcaaaccggauuagauacccggguaguccacgcccuaaacgaugcgcg
cuaggucucugggucuccugggggccgaagcuaacgcguuaagcgcgccg
ccuggggaguacggccgcaaggcugaaacucaaaggaauugacgggggcc
cgcacaagcgguggagcaugugguuuaauucgaagcaacgcgaagaaccu
uaccaggccuugacaugcuagggaacccgggugaaagccuggggugcccc
gcgaggggagcccuagcacaggugcugcauggccgucgucagcucgugcc
gugagguguuggguuaagucccgcaacgagcgcaacccccgccguuaguu
gccagcgguucggccgggcacucuaacgggacugcccgcgaaagcgggag
gaaggaggggacgacgucuggucagcauggcccuuacggccugggcgaca
cacgugcuacaaugcccacuacaaagcgaugccacccggcaacggggagc
uaaucgcaaaaaggugggcccaguucggauuggggucugcaacccgaccc
caugaagccggaaucgcuaguaaucgcggaucagccaugccgcggugaau
acguucccgggccuuguacacaccgcccgucacgccaugggagcgggcuc
uacccgaagucgccgggagccuacgggcaggcgccgaggguagggcccgu
gacuggggcgaagucguaacaagguagcuguaccggaaggugcggcugga
....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..<<<
.<<<..<<<..<<.<<<<<<<<<...>>>>>>>>>.>>>>>......<<.
......<<<<<<<<..<<...<<<<<<<.<<<<<....<<<<<......>
>>>>.....>>>>>...<<<<<.<<<<<....>>>>>.>>>>>..<<<<.
..>>>>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<<<<<....
...>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>
>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>>>>...
.....<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<....
..<<<<....>>>>.....>>>>....<<<<<........<<<<.....>
>>>..........>>>>>......<<<<<(((...<<<<<.....<<.))
)>>.......>>>>>>>>>>..>>>>>>>>>..........<<<((....
.<<<<...<<<.<<<<<<<.<<<<<<<<<<......<<<<<<.....>>>
>>>....>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<<<...
.<<<<<<<.<..<<<......>>>.....>.>>>>>>>...........<
<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<<<.
..<<...<<<<.<.....>.>>>>...>>>>>>>>..........<<<<<
<..<<<<<<<<<<...>>>>>>>>>>...<<..))>>.....>>>>>>.>
>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<.<<<<<
<<.<<.<<<<<<..<<<<<<<<<<......<<........>>........
..<<<<<<<......<<<<<<<<..<<<<<<<....>>>>>>>...<<<.
.....>>>..>>>>>>>>.<<<.<<<..<<<<<<.......<<<<<<<<<
....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<<..
.<...<<<.....>>>.>....>>>>>>>.....<<<<<....>>>>>..
......>>>>.........>>>...>>>>>>>>>...>>>>>>>...>>.
>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>..>>
....>>>.....>>>>>>>......<....<<<<<<<........>>>>>
>>....>.....>>>>>>....<<<<<<<..........>>>>>>>....
..>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<<<
<<<<<...<.<<<<....<<<....>>>.>>>>.>..>>>>>>>>>>>>>
..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>>>>>>...
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4p70 Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
Resolution3.68 Å
Binding residue
(original residue number in PDB)		Y20 H22 N26 N27 I29 T31 G37 N38 P39 W42 G46 G52 S53 K55 R85 V114 P115 H116 N117 G118 C119 R120 K122 K123 K124 K127
Binding residue
(residue number reindexed from 1)		Y10 H12 N16 N17 I19 T21 G27 N28 P29 W32 G36 G42 S43 K45 R75 V104 P105 H106 N107 G108 C109 R110 K112 K113 K114 K117
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4p70, PDBe:4p70, PDBj:4p70
PDBsum4p70
PubMed25128388
UniProtP80376|RS11_THET8 Small ribosomal subunit protein uS11 (Gene Name=rpsK)

[Back to BioLiP]