Structure of PDB 6gsl Chain Q8 Binding Site BS01

Receptor Information
>6gsl Chain Q8 (length=64) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PKMKTHKGAKKRVKITASGKVVAMKTGKRHLNWQKSGKEIRQKGRKFVLA
KPEAERIKLLLPYE
Ligand information
>6gsl Chain 1H (length=2895) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aagaugguaagggcccacgguggaugccucggcacccgagccgaugaagg
acguggcuaccugcgauaagccagggggagccgguagcgggcguggaucc
cuggauguccgaaugggggaacccggccggcgggaacgccggucaccgcg
cuuuuugcgcggggggaaccuggggaacugaaacaucucaguacccagag
gagaggaaagagaaaucgacucccugaguagcggcgagcgaaaggggacc
agccuaaaccguccggcuuguccgggcggggucguggggcccucggacac
cgaauccccagccuagccgaagcuguugggaagcagcgccagagagggug
aaagccccguaggcgaaagguggggggauaggugaggguacccgaguacc
ccgugguucguggagccaugggggaaucugggcggaccaccgccuaaggc
uaaguacuccgggugaccgauagcgcaccaguaccgugagggaaagguga
aaagaaccccgggaggggagugaaauagagccugaaaccgugggcuuaca
agcagucacggccccgcaagggguuguggcgugccuauugaagcaugagc
cggcgacucacggucgugggcgagcuuaagccguugaggcggaggcguag
ggaaaccgaguccgaacagggcgcaaacgggggccgaaaaguccgcggcc
guggacccgaaaccgggcgagcuagcccuggccagggugaagcuggggug
agacccaguggaggcccgaaccggugggggaugcaaaccccucggaugag
cuggggcuaggagugaaaagcuaaccgagcccggagauagcugguucucc
ccgaaaugacuuuagggucagccucaggcgcugacuggggccuguagagc
acugauagggcuagggggcccaccagccuaccaaacccugucaaacuccg
aagggucccagguggagccugggagugagggcgcgagcgauaacguccgc
guccgagcgcgggaacaaccgagaccgccagcuaaggcccccaagucugg
gcuaagugguaaaggauguggcgccgcgaagacagccaggauguuggcuu
agaagcagccaucauuuaaagagugcguaauagcucacuggucgaguggc
gccgcgccgaaaaugaucggggcuuaagcccagcgccgaagcugcggguc
ugggggaugaccccaggcgguaggggagcguucccgaugccgaugaaggc
cgacccgcgagggcggcuggagguaagggaagugcgaaugccggcaugag
uaacgauaaagagggugagaaucccucucgccguaagcccaaggguuccu
acgcaauggucgucagcguaggguuaggcgggaccuaaggugaagccgaa
aggcguagccgaagggcagccgguuaauauuccggcccuucccgcaggug
cgauggggggacgcucuaggcuagggggaccggagccauggacgagcccg
gccagaagcgcagggugggagguaggcaaauccgccucccaacaagcucu
gcgugguggggaagcccguacgggugacaaccccccgaagccagggagcc
aagaaaagccucuaagcacaaccugcgggaacccguaccgcaaaccgaca
caggugggcgggugcaagagcacucaggcgcgcgggagaacccucgccaa
ggaacucugcaaguuggccccguaacuucgggagaaggggugcucccugg
ggugaugagccccggggagccgcagugaacaggcucuggcgacuguuuac
caaaaacacagcucucugcgaacucguaagaggagguauagggagcgacg
cuugcccggugccggaaggucaaggggaggggugcaagccccgaaccgaa
gccccggugaacggcggccguaacuauaacgguccuaagguagcgaaauu
ccuugucggguaaguuccgaccugcacgaaaagcguaacgaccggagcgc
ugucucggcgagggacccggugaaauugaacuggccgugaagaugcggcc
uacccguggcaggacgaaaagaccccguggagcuuuacugcagccuggug
uuggcucuuggucgcgccugcguaggauaggugggagccugugaaccccc
gccuccgggugggggggaggcgccggugaaauaccacccuggcgcggcug
ggggccuaacccucggauggggggacagcgcuuggcgggcaguuugacug
gggcggucgccuccuaaaagguaacggaggcgcccaaagguccccucagg
cgggacggaaauccgccggagagcgcaaggguagaagggggccugacugc
gaggccugcaagccgagcaggggcgaaagccgggccuagugaaccggugg
ucccguguggaagggccaucgaucaacggauaaaaguuaccccggggaua
acaggcugaucucccccgagcguccacagcggcggggagguuuggcaccu
cgaugucggcucgucgcauccuggggcugaagaaggucccaaggguuggg
cuguucgcccauuaaagcggcacgcgagcuggguucagaacgucgugaga
caguucggucucuauccgccacgggcgcaggaggcuugaggggggcucuu
ccuaguacgagaggaccggaagggacgcaccucugguuucccagcugucc
cuccaggggcauaagcuggguagccaugugcggaagggauaaccgcugaa
agcaucuaagcgggaagcccgccccaagaugaggccucccacggcgucaa
gccgguaaggacccgggaagaccacccgguggaugggccggggguguaag
cgccgcgaggcguugagccgaccggucccaaucguccgaggucuu
.<<<......<<<<<<<<<<<.....<<..<<<<<<<<<<<<......<<
<<<<.((..((.>>>.....<<<<<<<..<<<))..)).>>>.....>>>
>>>>...>>>....<<<....>>><<<<<<<<....>>>>>>>>.<<<<<
<.....>>>>>>.>>...<<<<<<.....<......>......>>>>>.>
.........<<....>>...<<<<<.....<<.....>>....>>>>>..
.<<<....<<<<<<<<.....>>>>>>>>......<<<<<<<<<....<<
<...<<<<<.<<<<.<<<...<<<<<......>>>>>((......<<<..
...))>>>...>>>...>>>>..>>>>>..>>>>>>>>>.>>>.....<<
<<<<<<<.......>>>>>>>>>......<<<<<..((((>>>>>..>>>
......>>.>>>>>>.>>...............<<....>>....>>...
......<<<<....>>>>..................>>>>>>>>>>>...
....<<<<<<<<<<<....>>>>>>>>>>>...<............>.<<
<<<<....<<<<<<<<<<<<<..<<<...<<<.....>>>...>>>...<
<....>>..<<<<.....>>>>.....<<.....>>....>>>>>>>>>>
>>>..<<.<...<<<<<<.....<<<<<<<<<..<<<....<<<<<<...
...>>>>>>.....>>>...<<<..<<<<........>>>>.>>>....>
>>>>>>>>...<<<.....>>>......>>>>>>......>.>>..<<<<
<<....<<<<<....>>>>><<<<<<<<<.....<<<<<<<<<...<<<.
..<<<<<<<<.<.<<<<<<......>>>>.>>.>.>>>>>>>>..>>.>.
..>>>>>>>>>.....>>>>>>>.>>..<<<<<<<.<<......>>.>>>
>>>>.....<<<......>>>...<<<<.<<<...<<<(((.....<<<<
<<...........<<..<<<<<<<<<........<<<<<.<....<<<<.
......>>>>.....>........<<......>>...>>>>>....>>>>
>>>>>.>>..........)))......>>>>>>.>>>...>>>>>>><<<
<<<<<.....>>>>>>>>....>>>>>>..<<<<<...<<<......<<<
<<.<<<....>>>>>>>>...>>>..>>>>>........>>>>>><....
..<<.....<<<<<<.......>>>>>><<<<....<<<<<.<<...<<<
<<<...<<.....>>.>>>>>>....((<<<<.<<...<<<...<<<...
.>>>...>>>...>>...<<<<<........>>>>>))<<<<<<<<<<<<
<...<<<<....<<<<<.<<<..<<<<<.<<<<.<<..[[[[...>>>>>
><<<...<<<<<<<<<<<<<<<<.<<.....>>>>>>>>>.....>>>>>
>>>>..>>><...<<<<....>>>>.....>>>>>>...>>>..>>>>>.
........>>>>...>>...>>>>>>>>>>>>>>>..>>.....<<....
..>>>>>>>.<<<<<....>>>>>..>>>>..<<<<....<<<<<<<<.<
<.........<.....<<<<<.....<..>......>>>>><<<<<<<<<
<<<.....>>>>>>>>>>>>............<<<<<<<<<..<<<....
.....>>>..<<<<<<<.....<<<....>>>.......>>>>>>>.<<<
<<.<<<..<<<<<<<..<<<...<<...<<<<<....>>>>>...>>...
>>>>>>>>..>>>>><<<<<<.......>>>>>>........<.......
....<<<<<<.....>>>>>>.....>....>>>>>..>>.>>>>>>>..
>..>>.>>>>>>>>.>>>>>>.....>.....<<<<<........>>>>>
..<<<<<<<<.<<<.........<<<<.<<<<<<..<<<<<.<<<.<<<<
<.<<<<<<.<<<<<<<<<...........<<...<..<<......<<<<<
<<<....>>>>>>>>...>>.............>..>>..>>>>>>>>>.
>>>>>>...<<<<<....>>>>>....>>>>>.>>>..>>>>>..<<<<.
....>>>><<<<<<...........>>>>>>..<<...<<<<<<<...<<
<<<<.......>>>>>>.....<<...(((>>....>>>>>>>...<<<<
..<<<......>>>..>>>>.<<<....>>>.>>))).......<<<<<<
<.<<..))))..>>>>>>>>>.............>>>>..>>>>>>....
...<<<<..<<<<<<<...<<.......>>...>>>>>>>...>>>.>..
.....<<<<<.<<<<<<..<<<<<<<<<......>>>>>>>..>>.<<<<
<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>
>.>>>>........>>>>>>>>>>>....<<<<<<<...<<<<..<<<<<
<<...............>>>>>>>.<<<<<...<<<<...<<<<<<<<<<
<]]]]>>>>>>...>>>>>...>>>>.>>>>>...<<<....<<<<<...
........>>>>>....>>>.>>>>.......>>>>>>>..<<.......
..>>....<<<<<<<<<.......>>>>>....<<<<<<<<.<<<....<
<<<<....>>>>>...>>>..>>>>>.>>>...>>>>....>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6gsl Tautomeric G•U pairs within the molecular ribosomal grip and fidelity of decoding in bacteria.
Resolution3.16 Å
Binding residue
(original residue number in PDB)		P2 K3 M4 K5 T6 K8 K12 R13 K15 T17 A18 S19 K21 T27 K29 R30 H31 L32 N33 W34 K39 I41 R42 K44 R46 K47 F48 A51 P53 E54 R57 Y64
Binding residue
(residue number reindexed from 1)		P1 K2 M3 K4 T5 K7 K11 R12 K14 T16 A17 S18 K20 T26 K28 R29 H30 L31 N32 W33 K38 I40 R41 K43 R45 K46 F47 A50 P52 E53 R56 Y63
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6gsl, PDBe:6gsl, PDBj:6gsl
PDBsum6gsl
PubMed29931292
UniProtQ5SKU1|RL35_THET8 Large ribosomal subunit protein bL35 (Gene Name=rpmI)

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