Structure of PDB 6zvk Chain Q3 Binding Site BS01

Receptor Information

>6zvk Chain Q3 (length=63) Species: 9986 (Oryctolagus cuniculus)

KSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSVFMASHFDR
HYCGKCCLTYCFN

Ligand information

>6zvk Chain K3 (length=1869)

uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucgcuccucucccacuuggauaa
cugugguaauucuagagcuaauacaugccgacgggcgcugacccccuucg
cgggggggaugcgugcauuuaucagaucaaaaccaacccggucagccccu
cuccggccccggccggggggcgggcgccggcggcuuuggugacucuagau
aaccucgggccgaucgcacgccccccguggcggcgacgacccauucgaac
gucugcccuaucaacuuucgaugguagucgccgugccuaccauggugacc
acgggugacggggaaucaggguucgauuccggagagggagccugagaaac
ggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccacucccga
cccggggagguagugacgaaaaauaacaauacaggacucuuucgaggccc
uguaauuggaaugaguccacuuuaaauccuuuaacgaggauccauuggag
ggcaagucuggugccagcagccgcgguaauuccagcuccaauagcguaua
uuaaaguugcugcaguuaaaaagcucguaguuggaucuugggagcgggcg
ggcgguccgccgcgaggcgagccaccgcccguccccgccccuugccucuc
ggcgcccccucgaugcucuuagcugagugucccgcggggcccgaagcguu
uacuuugaaaaaauuagaguguucaaagcaggcccgagccgccuggauac
cgcagcuaggaauaauggaauaggaccgcgguucuauuuuguugguuuuc
ggaacugaggccaugauuaagagggacggccgggggcauucguauugcgc
cgcuagaggugaaauucuuggaccggcgcaagacggaccagagcgaaagc
auuugccaagaauguuuucauuaaucaagaacgaaagucggagguucgaa
gacgaucagauaccgucguaguuccgaccauaaacgaugccgaccggcga
ugcggcggcguuauucccaugacccgccgggcagcuuccgggaaaccaaa
gucuuuggguuccggggggaguaugguugcaaagcugaaacuuaaaggaa
uugacggaagggcaccaccaggaguggagccugcggcuuaauuugacuca
acacgggaaaccucacccggcccggacacggacaggauugacagauugau
agcucuuucucgauuccgugggugguggugcauggccguucuuaguuggu
ggagcgauuugucugguuaauuccgauaacgaacgagacucuggcaugcu
aacuaguuacgcgacccccgagcggucggcgucccccaacuucuuagagg
gacaaguggcguucagccacccgagauugagcaauaacaggucugugaug
cccuuagauguccggggcugcacgcgcgcuacacugacuggcucagcgug
ugccuacccuacgccggcaggcgcggguaacccguugaaccccauucgug
auggggaucggggauugcaauuauuccccaugaacgaggaauucccagua
agugcgggucauaagcuugcguugauuaagucccugcccuuuguacacac
cgcccgucgcuacuaccgauuggaugguuuagugaggcccucggaucggc
cccgccggggucggcccacggcccuggcggagcgcugagaagacggucga
acuugacuaucuagaggaaguaaaagucguaacaagguuuccguagguga
accugcggaaggaucauua

...<<<<<.{.((((>>>>><<<.<<<<<<...<.<<..<......<<<.
<<<..<<....<<...<<<..........>>>..>>.>>......<<...
.....<<<.<....<<....<<<<<..................<<.....
<<.<<<.....>>>.>>......>>.........<<<<...<<<<<<...
.>>>>>>...>>>>....<<<<<.....((.{......<<.....<<<.<
<<<<<........>>>>>>..>>>......>>.....<......>..>>>
>>...........<<<<.<<<<......>>>>>>>>.>>>.>>...>>..
>.>>>.<<<....<<<....<<<<<<<.........>>>>>>>>>>....
..>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<.........
.>>>.>>...<<....>>.....>>>>>>.........<<<....<<<<.
..>>>>..>>>..>...>>.>.....<<.<<<.<..<........>..>.
.>>>..>>......<<..<...........>..>>.........<<<<<(
(....<.<<<<.....<<..))>>.......>>>>>>>>>>..>>>>>>.
>>>.........<.<[[.....<.<<...<<<.<<.....<<.<<<<<<<
<.<<<<.<<<<....>>>>....>>>>.>>>..>>>>>>>........<<
<<.<<<<<...<<<<<<<......>>>>>>>....>>>>>>>>>.....<
<<<<<.<.......<<...<.......>.<<<<.......>>>>...>>.
.....>.>>>..>>>.......<<....<<<<<<<...........})).
>>>>>>>...>>....>>....<<<<<<......<<<<..<<..<<<<<<
<<...<<<......>>>......>>>>>>>>..>>.......<<....>>
...>>>>.....>>>.>>>...>>>...>>.>....<<<<<<....<...
<<<<.<.....>.>>>>...>.>>>>>>..........<<<.<<.<<<..
<.<<<<<<.<<<........>>>>>>>>>.>..>>>...<<..]]>>...
>>.....>>>.>.>.<<<......<<<<....>>>>....>>>..)))).
}<<<<<.<<<<<<...<<..<<<<<..<<<.<<<<<<......<<.....
...>>..........<<<<<.<....<<<<<<...........<<.....
...>>.........>>>>>>...<<.<<<..<<.<<<<<<....<<<.<<
<<<....>>>...<<<......>>>...>>.>>>....<<<...<...<<
<<..<<<.....<<.<..<<......>>>..>>.....>>>..>>>>..>
.....<<<<<.....>>>>>........>>>....>>>.>>>.....>>>
>>>>.....>.>>>>>...>>.>>>>.>>>.....<<.<<<.........
.......<<<.<<<<....>>>>.>>>..............>>>.>>...
.......<.<<<<<..........>>>>>>..........>>>>>.....
<<<<<<<<.......>>>>>>>>......>>....>>>>>>>>>.>>...
.<..<<.<..<<<<.<<....<<<<<<<<.<<<..<<<<.<<...<<<<<
<<<<<<<<<<<<.......>>>>>>>>>>>.>.>>>>>...>>.>>>>..
>>>.>>>>>>>>...>>.>>>>...>.>>...>.....<<<<<<<<<<..
>>>>>>>>>>.........

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6zvk The Halastavi arva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism.
• Resolution: 3.49 Å
• Binding residue (original residue number in PDB): K2 S3 Y4 T6 K8 K9 H12 K13 R14 K16 V17 K18 L19 A20 F50 H54 F55 D56 R57 Y59 G61 K62 T66
• Binding residue (residue number reindexed from 1): K1 S2 Y3 T5 K7 K8 H11 K12 R13 K15 V16 K17 L18 A19 F43 H47 F48 D49 R50 Y52 G54 K55 T59

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome

External links

• PDB: RCSB:6zvk, PDBe:6zvk, PDBj:6zvk
• PDBsum: 6zvk
• PubMed: 33296660
• UniProt: P79781|RS27A_CHICK Ubiquitin-ribosomal protein eS31 fusion protein (Gene Name=RPS27A)