Structure of PDB 9gaw Chain Q Binding Site BS01

Receptor Information
>9gaw Chain Q (length=505) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNLERLRKRVRQYLDQQQYQSALFWADKVASLSREEPQDIYWLAQCLYLT
AQYHRAAHALRSRKLDKLYEACRYLAARCHYAAKEHQQALDVLDMSQSSI
KSSICLLRGKIYDALDNRTLATYSYKEALKLDVYCFEAFDLLTSHHMLTA
QEEKELLESLPLSKLCNEEQELLRFLFENKLKKYNKPSETVIPESVDGLQ
ENLDVVVSLAERHYYNCDFKMCYKLTSVVMEKDPFHASCLPVHIGTLVEL
NKANELFYLSHKLVDLYPSNPVSWFAVGCYYLMVGHKNEHARRYLSKATT
LEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEY
GLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDA
LEKIKAIGNEVTVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQN
ASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHCIEMYIG
DSEAY
Ligand information
>9gaw Chain G (length=26) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
MLRRKPTRLELKLDDIEEFENIRKDL
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9gaw High-resolution structure of the Anaphase-promoting complex (APC/C) bound to co-activator Cdh1
Resolution2.9 Å
Binding residue
(original residue number in PDB)
Y242 Y243 I338 H342 A345 Y357 Y373 L376 E377 F403 H406 E407 V410 F413 E445 N449 N450 H453 R456 K457 N478 T481 Y487 F514 M518 M525
Binding residue
(residue number reindexed from 1)
Y214 Y215 I310 H314 A317 Y329 Y345 L348 E349 F375 H378 E379 V382 F385 E417 N421 N422 H425 R428 K429 N450 T453 Y459 F486 M490 M497
External links
PDB RCSB:9gaw, PDBe:9gaw, PDBj:9gaw
PDBsum9gaw
PubMed
UniProtQ13042|CDC16_HUMAN Cell division cycle protein 16 homolog (Gene Name=CDC16)

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