Structure of PDB 8se7 Chain Q Binding Site BS01

Receptor Information
>8se7 Chain Q (length=193) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DPNSLRHKYNFIADVVEKIAPAVVHIELFRKLPFSREVPVASGSGFIVSE
DGLIVTNAHVVTNKHRVKVELKNGATYEAKIKDVDEKADIALIKIDHQGK
LPVLLLGRSSELRPGEFVVAIGSPFSLQNTVTTGIVSTTDYIQTDAIINY
GNAGGPLVNLDGEVIGINTLKVGISFAIPSDKIKKFLTESHDR
Ligand information
>8se7 Chain T (length=29) Species: 3679 (Ecballium elaterium) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PICNKPCKTHDDCAWFCQTCYYATWSCGW
Receptor-Ligand Complex Structure
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PDB8se7 HTRA-1 PDSA bound to CKP 1A8
Resolution2.96 Å
Binding residue
(original residue number in PDB)
I186 P200 V201 A202 S203 G204 S205 T217 N218 H220 V221 Y325
Binding residue
(residue number reindexed from 1)
I26 P39 V40 A41 S42 G43 S44 T56 N57 H59 V60 Y150
External links
PDB RCSB:8se7, PDBe:8se7, PDBj:8se7
PDBsum8se7
PubMed
UniProtQ92743|HTRA1_HUMAN Serine protease HTRA1 (Gene Name=HTRA1)

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