Structure of PDB 8pk0 Chain Q Binding Site BS01

Receptor Information
>8pk0 Chain Q (length=221) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ERRFLSPEFIPRRGRTDPLKFQIERKDMLERRKVLHIPEFYVGSILRVTT
ADPYASGKISQFLGICIQRSGRGLGATFILRNVIEGQGVEICFELYNPRV
QEIQVVKLEKRLDDSLLYLRDALPEYSTFDVNMKPVVQEPNQKVPVNELK
VKMKPKPWSKRWERPNFNIKGIRFDLCLTEQQMKEAQKWNQPWLEFDMMR
EYDTSKIEAAIWKEIEASKRS
Ligand information
>8pk0 Chain A (length=1423) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccagacaaccuuagc
caaaccauuuacccaaauaaaguauaggcgauagaaauugaaaccuggcg
caauagauauaguaccgcaagggaaagaugaaaaauuauaaccaagcaua
auauagcaaggacuaaccccuauaccuucugcauaaugaauuaacuagaa
auaacuuugcaaggagagccaaagcuaagacccccgaaaccagacgagcu
accuaagaacagcuaaaagagcacacccgucuauguagcaaaauaguggg
aagauuuauagguagaggcgacaaaccuaccgagccuggugauagcuggu
uguccaagauagaaucuuaguucaacuuuaaauuugcccacagaacccuc
uaaauccccuuguaaauuuaacuguuaguccaaagaggcucuuuggacac
uaggaaaaaaccuuguagagagaguaaaaaauuuaacacccauaguaggc
cuaaaagcagccaccaauuaagaaagcguucaagcucaacacaaauccca
aacauauaacugaacuccucacacccaauuggaccaaucuaucacccuau
agaagaacuaauguuaguauaaguaacaugaaaacauucuccuccgcaua
agccugcgucagauuaaaacacugaacugacaauuaacagcccaauaucu
acaaucaaccaacaagucauuauuacccucacugucaacccaacacaggc
augcucauaaggaaagguuaaaaaaaguaaaaggaacucggcaaaucuua
ccccgccuguuuaccaaaaacaucaccucuagcaucaccaguauuagagg
caccgccugcuauauauauauauauauauauauauauauauuggcuccac
gaggguucagcugucucuuacuuuuaaccagugaaauugaccugcccgug
aggcgggcauaacacagcaagacgagaagacccuauggagcuuuaauuua
uuaaugcaaacagaaaccugcauuaaaaauuucgguuggggcgaccucgg
agcagaacccaaccuccgagcaguacaugcuaagacuucaccagucaaag
cgaacacucaauugauccaauaacuugaccaacggaacaaguuacccuag
ggacgcaauccuauucuagaguccauaucaacaauaggguuuuggaucag
gacaucccgauggugcagccgcuauuaaagguucguuuguucaacgauua
aaguccuacgugaucugaguucagaccggaguaauccaggucgguuucua
ucuacuuucaaauuccucccuguacgaaaggacaagagaaauaaggccua
cuucacaaagcgccuucccccguaaaugauaucaucucaacuuaguauac
ccaccccacccaagaacaggguu
<<<.......<<<<....................................
.<......>.........<.....<<.....>>....>........>>.>
>.............<<....>>......................>>>...
........<<<.......>>>...<.<........>.>.<<<<<<.....
....<<<.<<..<<....>>...>>.>>>...<<.<...<<<<.<.....
<<<<<.<<<..<<<.....>>>...<<<..<<<<........>>>>.>>>
....>>>.>>>>>...<<.......>>......>.>>>>......>.>>.
.<<<<<<....<<<<....>>>><<<.<<<<<<<<<<.....<<......
....>>.....>>>>>>>>>>..>>>.<<<<<<<<<...>>>>>>>>>..
.<<<......>>>....<<<.<<<...<..............<....<<<
.........>>>....>.......<<<......>>>..............
..........>...>>>>>>........>>>>>>...<<<<<......>>
>>>.........>>>>>><......<<..<<<....>>><<<<..<<<<.
.......<<<<<..............>>>>>......<<<...<<<<...
....................>>>>.......>>>.....<<......>>.
>>>>.....>>>>..<<<<...<<<<<<<<.<<................<
<<<<<..<<<.........>>>...<<<<<<.............>>>>>>
....<<<...<<<<<<..>>>>>>.<<<<<<<..>>>>>>>.>>>....>
>.>>>>........>>.>>>>>>>>>>>>.>>.....>.....<<<<<..
...>>>>>.......<<..<<<........<<<<<.<<<<<<..<<<<<.
<<<<<<<<..........>>>>>>>>>>>>>..<<<<.....>>>><<<<
<<...........>>>>>>..<<.....<<<..<<<<.....>>>>..>>
>.....>>.........<<<....>>>............>>>>..>>>>>
>>....<<<<<<<<<...<<.......>>...>>>>>>>>><<<<<.<<<
<<<..<<.<<<<<<......>>>>>>...>>.<<<<<.....>>>>>...
..>>>>>..>...>>>>>.....<<<<<<<....>>>.>>>>........
>>>.>>...<.<<<.<<<.................>>>.>>><<<<<...
<<<....>>>.>>>>>......<<<................>>>...>..
.......<<<<.......>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8pk0 Structural insights into the role of GTPBP10 in the RNA maturation of the mitoribosome.
Resolution3.03 Å
Binding residue
(original residue number in PDB)		R83 R84 R86 Q139 S141 G146 T148 K231 R232 R235
Binding residue
(residue number reindexed from 1)		R12 R13 R15 Q68 S70 G75 T77 K160 R161 R164
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8pk0, PDBe:8pk0, PDBj:8pk0
PDBsum8pk0
PubMed38042949
UniProtP49406|RM19_HUMAN Large ribosomal subunit protein bL19m (Gene Name=MRPL19)

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