Structure of PDB 8phj Chain Q Binding Site BS01

Receptor Information
>8phj Chain Q (length=79) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KIRTLQGRVVSDKMEKSIVVAIERFVKHPIYGKFIKRTTKLHVHDENNEC
GIGDVVEIRECRPLSKTKSWTLVRVVEKA
Ligand information
>8phj Chain A (length=1503) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aauugaagaguuugaucauggcucagauugaacgcuggcggcaggccuaa
cacaugcaagucgaacgguaacaggaaguuugcugacgaguggcggacgg
gugaguaaugucugggaaacugccugauggagggggauaacuacuggaaa
cgguagcuaauaccgcauaacgucgcaagaccaaagagggggccucuugc
caucggaugugcccagaugggauuagcuaguaggugggguaacggcucac
cuaggcgacgaucccuagcuggucugagaggaugaccagccacacuggaa
cugagacacgguccagacuccuacgggaggcagcaguggggaauauugca
caaugggcgcaagccugaugcagccaugccgcguguaugaagaaggccuu
cggguuguaaaguacuuucagcggggaggaagggaguaaaguuaauaccu
uugcucauugacguuacccgcagaagaagcaccggcuaacuccgugccag
cagccgcgguaauacggagggugcaagcguuaaucggaauuacugggcgu
aaagcgcacgcaggcgguuuguuaagucagaugugaaauccccgggcuca
accugggaacugcaucugauacuggcaagcuugagucucguagagggggg
uagaauuccagguguagcggugaaaugcguagagaucuggaggaauaccg
guggcgaaggcggcccccuggacgaagacugacgcucaggugcgaaagcg
uggggagcaaacaggauuagauacccugguaguccacgccguaaacgaug
ucgacuuggagguugugccggcguggcuuccggagcuaacgcguuaaguc
gaccgccuggggaguacggccgcaagguuaaaacucaaaugaauugacgg
gggcccgcacaagcgguggagcaugugguuuaauucgaugcaacgcgaag
aaccuuaccuggucuugacauccacggaaguuuucagagaugagaaugug
ccgaaccgugagacaggugcugcauggcugucgucagcucguguugugaa
auguuggguuaagucccgcaacgagcgcaacccuuauccuuuguugccag
cgguccggccgggaacucaaaggagacugccagugauaaacuggaggaag
guggggaugacgucaagucaucauggcccuuacgaccagggcuacacacg
ugcuacaauggcgcauacaaagagaagcgaccucgcgagagcaagcggac
cucauaaagugcgucguaguccggauuggagucugcaacucgacuccaug
aagucggaaucgcuaguaaucguggaucagaaugccacggugaauacguu
cccgggccuuguacacaccgcccgucacaccaugggaguggguugcaaaa
gaaguagguagcuuaaccuucgggagggcgcuuaccacuuugugauucau
gacuggggugaagucguaacaagguaaccguaggggaaccugcgguugga
uca
.......<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....
<<<.<<<..<<<..<<.<...<<<<<<.>>>.>>>.>..>>>>>......
<<.......<<<<<<<..<<...<<<<<<<.<.<<.....<<<<<.....
.>>>>>......>>.>.....<<<....>>>....<<<<<<.>>>>>>.>
>>>>>>..>>.>>>>>>><<<....<<<..<<<<<<<.........>>>>
>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>.<<<<<.
<.........>>>>>>.<<<<....>>>>...>>>>>>.........<<<
....<<<<....>>>>..>>>..>>.>>>>>>..<<<<......<<<<<.
.>>>>>.....>>>>...<.<<<<<......<.<<<<<<<<.......>>
>>>>>>.>........>>>>>....>..<<<<<(((...<<<<<.....<
<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<<((
.....<<<<...<<<.<<<<<<<.<<<<<<<<<<......<<<<<<....
.>>>>>>....>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<<
<....<<<<<<<<...<<<......>>>......>>>>>>>>........
...<<....>>.>>>>>>>..>>>>.>>>>...>>>...>>>>....<<<
<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>..........<
<<<<<.<<<<<<<<<<<<..>>>>>>>>>>>>..<<..))>>.....>>>
>>>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<.
<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>...
.......<<<<<<<......<<<<<<<..<<<<<<<....>>>>>>>...
.....>>>>>.>>.<<<.<<<..<<<<<<.......<<<<<<<<<....>
>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<<...<<..
<<<.....>>>>>....>>>>>>>.....<<<<<.....>>>>>......
..>>>>.........>>>...>>>>>>>>>...>>>>>>>...>>.>>>>
>>>>.....<<<<<<<.....<<<..<<...<<<....>>>...>>....
>>>.....>>>>>>>......<....<<<<<<<........>>>>>>>..
..>.....>>>>>>....<<<<<<<.........>>>>>>>......>>.
..>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<<<<<<<.
...<<<<<<.<<<<..<<....>>.>>>>>>>>>>...>>>>>>>>>>>>
..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>>>>>>...
...
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8phj Ribosomal stalk-captured CARF-RelE ribonuclease inhibits translation following CRISPR signaling
Resolution3.67 Å
Binding residue
(original residue number in PDB)		K4 S14 K16 M17 E18 K19 R27 R40 T41 K43 H45 E63 R65 P66 S68 K69 T70 K71 S72
Binding residue
(residue number reindexed from 1)		K1 S11 K13 M14 E15 K16 R24 R37 T38 K40 H42 E60 R62 P63 S65 K66 T67 K68 S69
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0008270 zinc ion binding
GO:0019843 rRNA binding
GO:0070181 small ribosomal subunit rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0046677 response to antibiotic
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8phj, PDBe:8phj, PDBj:8phj
PDBsum8phj
PubMed38033086
UniProtP0AG63|RS17_ECOLI Small ribosomal subunit protein uS17 (Gene Name=rpsQ)

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