Structure of PDB 8p03 Chain Q Binding Site BS01

Receptor Information
>8p03 Chain Q (length=136) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKAD
RDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSA
LRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL
Ligand information
>8p03 Chain 2 (length=1743) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcuacuuggauaacugugguaauuc
uagagcuaauacaugccgacggcgcugacucccuuugugugggaugcgug
cauuuaucagaucaaaaccaacccggucggcggcuuuggugacucuagau
aaccucgggccgaucgcagcccuccguggcggcgacgacccauucgaacg
ucugcccuaucaacuuucgaugguagucgccgugccuaccauggugacca
cgggugacggggaaucaggguucgauuccggagagggagccugagaaacg
gcuaccacauccaaggaaggcagcaggcgcgcaaauuacccacucccgac
ccggggagguagugacgaaaaauaacaauacaggacucuuucgaggcccu
guaauuggaaugaguccacuuuaaauccuuuaacgaggauccauuggagg
gcaagucuggucgcagcagccgcgguaauuccagcuccaauagcguauau
uaaaguugcugcaguuaaaaagcucguaguuggaucuuguggaggguucc
ccgccccuugccucucggcgccggcccgaagcguuuacuuugaaaaaauu
agaguguucaaagcaggcccgagccgccuggauaccgcagcuaggaauaa
uggaauaggaccgcgguucuauuuuguugguuuucggaacugaggccaug
auuaagagggacggccgggggcauucguauugcgccgcuagaggugaaau
ucuuggaccggcgcaagacggaccagagcgaaagcauuugccaagaaugu
uuucauuaaucaagaacgaaagucggagguucgaagacgaucagauaccg
ucguaguuccgaccauaaacgaugccgacuggcgaugcggcggcguuauu
cccaugacccgccgggcagcuuccgggaaaccaaagucuuuggguuccgg
ggggaguaugguugcaaagcugaaacuuaaaggaauugacggaagggcac
caccaggaguggagccugcggcuuaauuugacucaacacgggaaaccuca
cccggcccggacacggacaggauugacagauugauagcucuuucucgauu
cugugggugguggugcauggccguucuuaguugguggagcgauuugucug
guuaauuccgauaacgaacgagacucuggcaugcuaacuaguuacgcgac
ccccgagcggucggcgucccccaacuucuuagagggacaaguggcguuca
gccacccgagauugagcaauaacaggucugugaugcccuuagaugucggg
gcugcacgcgcgcuacacugacuggcucagcgugugccuacccuacgccg
gcaggcgcggguaacccguugaaccccauucgugauggggaucggggauu
gcaauuauuccccaugaacgaggaauucccaguaagugcgggucauaagc
uugcguugauuaagucccugcccuuuguacacaccgcccgucgcuacuac
cgauuggaugguuuagugaggcccucggaucggcccgccggggugcccug
gcggagcgcugagaagacggucgaacuugacuaucuagaggaaguaaaag
ucguaacaagguuuccguaggugaaccugcggaaggaucauua
...<<<<<...[[[[>>>>>[[[.((((((.....{{.........[[[.
[[[..<<....<<....<<..........>>...>>.>>......{{...
.....[[[......{{....[[[........<<.....<<.<<<.....>
>>.>>......>>.........<<<...<<.<......>.>>...>>>.[
[..(((((......<<<<<<<<<<<.....>>>....<......>..)))
))......]]...<<<<.<<<......>>>.>>>>....]]]...}}...
.]]].<<<....<<<....<<<<<<<.........>>>>>>>>>>.....
.>>>...<<<.<<<<....>>>>....>>>.}}.<<.<<<..........
>>>.>>.<.<<....>>.>...]]]]]].........<<<....<<<<..
.>>>>..>>>......}}.......<<<<<..<<.<<<....>>>.>>..
.>>.>>>......<<..<...........>..>>.........<<<<<((
....<.<<<<.....<<..))>>.......>>>>>>>>>>..)))))).]
]]............{{.......{{...[[[.[[....<<<<.<<...>>
>>>>......<...<....<<..>>...>.>...<<<<<<.<.......<
<...<.......>.<<<<.......>>>>...>>......>.>>>..>>>
.......[[....(((((((.....>>>>>>>>..)))))))...]]...
.]]....<<<<<<..<...<<<<..<<..<<<<<<<<...<<<......>
>>......>>>>>>>>..>>.......<<....>>...>>>>..>..>>>
.>>>...]]]...}}......<<<<<<<...<...<<<<.<.....>.>>
>>...>>>>>>>>..........<<<.<<.<<<..<.<<<<<<.<<<<<.
...>>>>>>>>>>>.>..>>>...<<..}}>>...>>.....>>>.....
<<<......<<<<....>>>>....>>>..]]]]..<<<<<.<<<<<<<.
.<<..<<<<<..<<<.<<<<<<......<<........>>..........
<<<<<......<<<<<<.......<<.<<<........>>>.>>.....>
>>>>>.<.<<.<<<..<<.<<<<<<....<<<.<<<<<....>>>...<<
<......>>>...>>.>>>....<<<...<...<<<<..<<<<....<..
.<.<<<....>>>>...>....>>>>..>>>>..>.....<<<<<.....
>>>>>........>>>....>>>.>>>.....>>>>>>>>.....>>>>>
...>>.>>>>.>>>.....<<.<<<........<.......<<<.<<<<.
...>>>>.>>>....>.........>>>.>>......<.....<<<<<..
........>>>>>.....>.....>>>>>.....<<<<<<<<.......>
>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<..<<<<.<
<....<<<<<<<<.<<<..<<<<.<<...<<<<<.<<<<<<<<..>>>>>
>>.>...>>>>>...>>.>>>>..>>>.>>>>>>>>...>>.>>>>...>
.>>...>.....<<<<<<<<<<..>>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8p03 N 6 -methyladenosine in 5' UTR does not promote translation initiation.
Resolution3.04 Å
Binding residue
(original residue number in PDB)		N38 D39 H43 G49 K50 T52 R55 T57 G59 D65 R66 R104 I135 P136 S137 D138 R141 K143 G144 G145 R146 R147 R149 R150 L151
Binding residue
(residue number reindexed from 1)		N23 D24 H28 G34 K35 T37 R40 T42 G44 D50 R51 R89 I120 P121 S122 D123 R126 K128 G129 G130 R131 R132 R134 R135 L136
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8p03, PDBe:8p03, PDBj:8p03
PDBsum8p03
PubMed38244546
UniProtG1T1F0|RS14_RABIT Small ribosomal subunit protein uS11 (Gene Name=RPS14)

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