Structure of PDB 8g8n Chain Q Binding Site BS01

Receptor Information
>8g8n Chain Q (length=211) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EIVLTQSPDFQSVTPKEKVTITCSAALSYMYWYQQKPDQSPKLWVHGTSN
LASGVPSRFSGSGSGTDFTLTINSLEAEDAATYYCHHWSNTQWTFGGGTK
VEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNA
LQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSS
PVTKSFNRGEC
Ligand information
Receptor-Ligand Complex Structure
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PDB8g8n XTX101, a tumor-activated, Fc-enhanced anti-CTLA-4 monoclonal antibody, demonstrates tumor-growth inhibition and tumor-selective pharmacodynamics in mouse models of cancer.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		W91 W96
Binding residue
(residue number reindexed from 1)		W88 W93
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