Structure of PDB 8d8l Chain Q Binding Site BS01

Receptor Information

>8d8l Chain Q (length=204) Species: 4932 (Saccharomyces cerevisiae)

ARQNFLGLVVSQGKMQKTVKVRVETKVFNKKINKELFHRRDYLVHDEGEI
SREGDLVRIEATRPLSKRKFFAIAEIIRNKGQQFALYESEAQLSVAKEEA
QKAKEFLDKRSVRENKLLRDIRTIQDALTPKELLEIKQRETVRQLLQLDI
SGLEVNLEKQRSLIDRIQTRLSELLSNDLKCDQFLKDHGNIKKNLLRKHV
MMDM

Ligand information

>8d8l Chain a (length=1506)

uaagaauaugauguugguucagauuaagcgcuaaauaaggacaugacaca
ugcgaaucauacguuuauuauugagauaauaaauaugugguguaaacgug
aguaauuuuauuaggaauuaaugaacuauagaauaagcuaaauacuuaau
auuauauaaaaauaauuuauauaauaaaaaggauauauauauauauauuu
aucuauagucaagccaauaaugguuuagguaguagguuuauuaagaguua
aaccuagccaacgauccauaaucgauaaugaaaguuagaacgaucacguu
gacucugaaauauagucaauaucuauaagauacagcagugaggaauauug
gacaaugaucgaaagauugauccaguuacuuauuaggaugauauauauau
auauauaaauugauuaaaaauaaaauccauaaauaauuaaaauaaugaua
uuaauuaccauauauuuauauggauauauauauauuuuaauaguccugac
uaauauuugugccagcagucgcgguaacacaaagagggcgagcguuaauc
auaaugguuuaaaggauccguagaaugaauuauauauaauuuagaguuaa
uaaaauauaauuaaagaauuauaauaguaaagaugaaauaauaauaauaa
uuauaagacuaauauaugugaaaauauuaauuaaauauuaacugacauug
agggauuaaaacuagaguagcgaaacggauucgauacccguguaguucua
guaguaaacuaugaauacaauuauuuauaauauauauauaaauaauaaau
gaaaaugaaaguauuccaccugaagaguacguuagcaauaaugaaacuca
aaacaauagacgguuacagacuuaagcaguggagcauguuauuuaauucg
auaauccacgacuaaccuuaccauauuuugaauauuauaauaauuauaau
uauuauauuacaggcguuacauuguugucuuuaguucgugcugcaaaguu
uuagauuaaguucauaaacgaacaaaacuccauauauauaauuuuaauua
uauauaauuuuauauuauuuauuaauauaaagaaaggaauuaagacaaau
cauaaugauccuuauaauauggguaauagacgugcuauaauaaaaugaua
auaaaauuauauaaaauauauuuaauuauauuuaauuaauaauauaaaac
auuuuaauuuuuaauauauuuuuuuauuauaauaugaauuauaaucugaa
auucgauuauaugaaaaaagaauugcuaguaauacguaaauuaguauguu
acggugaauauucuaacuguuucgcacuaaucacucaucacgcguugaaa
cauauuauuaucuuauuauuuauauaauauuuuuuaauaaauauuauuaa
uuuauauuuauuuauaucagaaauaauaugaauuaaugcgaaguugaaau
acaguuaccguaggggaaccugcggugggcuuauaaauaucuuaaauauu
cuuaca

...<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<......<<<.
<<<..<<<..<<<<<<<<<<<<..>>>>>>>>>>..>>>>>.....<<<.
.......<<<<<.<<.........<<<<<<<<.<<<<.......>>>>..
.<<<<<<<<<.....>>>>>>>>>......<<<<<<<<<..>>>>>>>>>
.>>>>>>>>....>>>>>>><<<....<<<..<<<<<<<<........>>
>>>>>>>>>......>>>..<<<<.<<<<....>>>>...>>>>.>>><<
<<<<.........>>>>>><<<<.....>>>>..>>>>>>.........<
<<...<<<<<....>>>>.>>>>...>.>>>>>>.<<<<..<<<<<<...
.>>>>>>..<<......>>.....>>>>..<<<<<<<<............
..>>>>><<<<<<<..>>>>>>>.<<<<..>>>>.>>>....<<<<<(((
.....<<<<.....<<.)))>>.......>>>>.>>>>>..>>>>>>>>>
.....<<<((.....<<<<...<.<<.<<<<<<..>>>>>>...<<<<<<
<<.....<<<<<<<<<..<<<<<<<....<...........>.......>
>>>>>>..>>.......<<....>>.>>>>>>>..>>>>>>>>...>>>.
..>>>>....<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>>
>>..........<<<<<<.<<<<<<<<<<<<..>>.>>>>>>>>>>..<<
..))>>....>>>>>>.>>>.<<.......<<<<....>>>>.....>>.
.)))).]<<.<<...<<<<......<<<<<..<<<<<<<<<<........
....................<<<<<<<.....<<.<<<<<<<<<<..>>>
>>>>>>>.>>.<<<.<<..<<<<<<<<<<<<..<<<<<<<<<....>>>.
...<<......>>....>>>>>>.....<<<.<<<<<<<<........>>
>>>>>>..<<<<<<<<<.....>>>>>>>>>....>>>...>>>>>>>..
..>>>>>>>>>>...>>>>>>>...>>.>>>>>>>>.....<<<<<<...
.....<<<..<<..<<<<<<......>>>>>>..>>....>>>......>
>>>>>......<<<<<.<....>.>>>>>.....<....<<<<<<<....
....>>>>>>>....>.....>>>>>.....<<.<<<<<.........>>
>>>>>...........>>>>..>>..>>....<.<<<.<.<<<<<<<<..
<<<<<<<<<.<<<...<<<..<<<.<<<<<...<<<<<<<...>>>>>>>
...>>>>>>>>..>>>..>>>>>>>>>>>>..>>>>>>>>..>.>>.>.>
.....<<<<<<<<<....>>>>>>>>>.......................
......

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8d8l Principles of mitoribosomal small subunit assembly in eukaryotes.
• Resolution: 2.6 Å
• Binding residue (original residue number in PDB): A2 R3 Q4 K15 M16 Q17 T19 K21 K31 K35 F38 H39 R40 R41 R64 P65 L66 S67 K68 R69 K70 F71 F72
• Binding residue (residue number reindexed from 1): A1 R2 Q3 K14 M15 Q16 T18 K20 K30 K34 F37 H38 R39 R40 R63 P64 L65 S66 K67 R68 K69 F70 F71

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation
• GO:0030435 sporulation resulting in formation of a cellular spore
• GO:0032543 mitochondrial translation

Cellular Component

• GO:0005739 mitochondrion
• GO:0005743 mitochondrial inner membrane
• GO:0005763 mitochondrial small ribosomal subunit
• GO:0005840 ribosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8d8l, PDBe:8d8l, PDBj:8d8l
• PDBsum: 8d8l
• PubMed: 36482135
• UniProt: Q03246|RT17_YEAST Small ribosomal subunit protein uS17m (Gene Name=MRPS17)