Structure of PDB 8adl Chain Q Binding Site BS01

Receptor Information
>8adl Chain Q (length=782) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPYNSPTFGKSLSLKVDGGFNAVSINPSGRDIVLASRQGLYIIDLDDPFT
PPRWLHHITPWQVADVQWSPHPAKPYWIVSTSNQKAIIWNLAKSSSNAIE
FVLHGHSRAITDINFNPQHPDVLATCSVDTYVHAWDMRSPHRPFYSTSSW
RSAASQVKWNYKDPNVLASSHGNDIFVWDLRKGSTPLCSLKGHVSSVNSI
DFNRFKYSEIMSSSNDGTVKFWDYSKSTTESKRTVTTNFPIWRGRYLPFG
EGYCIMPMVGGNNAVYLINLCDDNKKTKLQPIYAFKGHSDRVIDFLWRSR
HTCDGDYDDREFQLVTWSKDCDLKLWPISDSIYGKVNFDRGKRLEEKLPD
YDYCSYNKEPENFRRLRENFVTTSGLKTNHITWLSGIRMNIQNLGEEVSA
IGHKFPKVVFEKISVSTRELCLTLNGPWSEENPDDYIFLRISINFPLNYP
NKGDPPKFTIEENSNLTMSKRQEILSNLATIGQKYTDSNLYCLEPCIRFV
LGETTPVPNGCGSCWTATGELFCFFANKNLVISKNFSSLLSDRKELALEY
LFMDATPEGFARNNALVAEKFDLDEISHCWQILSDMLIDQSDYDPYTTIW
NNHPMGIKWFIKEAIVYFERQQNLQMLAMLCCVILSARRMPDIKVELLHD
DIIEAYEQEDLLHLEVSDIPKFQTYIYQYSKLLFRWGLPLERVKILKVST
DFRSSYSSPYNGVLTHWIENNEFGEEKFLARNCNYCDLRVTRSSFICGNC
QHVLHSSCARIWWEIGDECPSGCGCNCPEMFD
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8adl Chain Q Residue 1201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8adl Cryo-EM structure of the SEA complex.
Resolution2.95 Å
Binding residue
(original residue number in PDB)		C1098 C1101 H1120 C1123
Binding residue
(residue number reindexed from 1)		C733 C736 H755 C758
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0035591 signaling adaptor activity
Biological Process
GO:0015031 protein transport
GO:0034198 cellular response to amino acid starvation
GO:1903432 regulation of TORC1 signaling
GO:1904263 positive regulation of TORC1 signaling
Cellular Component
GO:0000329 fungal-type vacuole membrane
GO:0005773 vacuole
GO:0005774 vacuolar membrane
GO:0016020 membrane
GO:0035859 Seh1-associated complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8adl, PDBe:8adl, PDBj:8adl
PDBsum8adl
PubMed36289347
UniProtQ03897|WDR59_YEAST Maintenance of telomere capping protein 5 (Gene Name=MTC5)

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