Structure of PDB 7zs9 Chain Q Binding Site BS01

Receptor Information
>7zs9 Chain Q (length=221) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NASPFIKRDRMRRNFLRMRDPNEYNEFPLRAIPKEDLENMRTHLLKFQSK
KKINPVTDFHLPVRLHRKDTRNLQFQLTRAEIVQRQKEISEYKKLRRKTR
QLKVLDENAKKLRFEEFYPWVMEDFDGYNTWVGSYEAGNSDSYVLLSVED
DGSFTMIPADKVYKFTARNKYATLTIDEAEKRMDKKSGEVPRWLMKHLDN
IGTTTTRYDRTRRKLKAVADQ
Ligand information
>7zs9 Chain N (length=209) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agcacgctgtgtatataatagctatggaacgttcgattcacctccgatgt
gtgttgtacatacataaaaatatcatagctcttctgcgctgtgttggtcg
tagacagctctagcaccgcttaaacgcacgtacgcgctgtcccccgcgtt
ttaaccgccaaggggattactccctagtctccaggcacgtgtcagatata
tacatcgat
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7zs9 Structures of transcription preinitiation complex engaged with the +1 nucleosome.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		K411 K416
Binding residue
(residue number reindexed from 1)		K181 K186
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001096 TFIIF-class transcription factor complex binding
GO:0003677 DNA binding
GO:0016251 RNA polymerase II general transcription initiation factor activity
GO:0072542 protein phosphatase activator activity
Biological Process
GO:0001174 transcriptional start site selection at RNA polymerase II promoter
GO:0006355 regulation of DNA-templated transcription
GO:0006367 transcription initiation at RNA polymerase II promoter
GO:0006368 transcription elongation by RNA polymerase II
GO:0032968 positive regulation of transcription elongation by RNA polymerase II
GO:0051123 RNA polymerase II preinitiation complex assembly
Cellular Component
GO:0005634 nucleus
GO:0005674 transcription factor TFIIF complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7zs9, PDBe:7zs9, PDBj:7zs9
PDBsum7zs9
PubMed36411341
UniProtP41895|T2FA_YEAST Transcription initiation factor IIF subunit alpha (Gene Name=TFG1)

[Back to BioLiP]