Structure of PDB 7vyf Chain Q Binding Site BS01

Receptor Information
>7vyf Chain Q (length=386) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SNLTLNFGPQHPAAHGVLRLVMELSGEMVRKCDPHIGLLHRGTEKLIEYK
TYLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIQPPPRAQWIRVLFGEI
TRLLNHIMAVTTHALDIGAMTPFFWMFEEREKMFEFYERVSGARMHAAYI
RPGGVHQDLPLGLLDDIYEFSKNFSFRIDELEEMLTNNRIWRNRTVDIGV
VTAEDALNYGFSGVMLRGSGIQWDLRKTQPYDVYDQVEFDVPIGSRGDCY
DRYLCRVEEMRQSLRIISQCLNKMPPGEIKVDDAKVSPPKRAEMKTSMES
LIHHFKLYTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPYRCKIKAP
GFAHLAGLDKMSKGHMLADVVAIIGTQDIVFGEVDR
Ligand information
>7vyf Chain W (length=29) Species: 9823 (Sus scrofa) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ASKVKQDMPPPGGYGPIDYKRNLPRRGLS
Receptor-Ligand Complex Structure
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PDB7vyf The coupling mechanism of mammalian mitochondrial complex I.
Resolution2.8 Å
Binding residue
(original residue number in PDB)
R166 D235 P237 L238 L240 L241 D242 Y245 S248 S252 D256 E259 R338 L348 P353 G354
Binding residue
(residue number reindexed from 1)
R89 D158 P160 L161 L163 L164 D165 Y168 S171 S175 D179 E182 R261 L271 P276 G277
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0048038 quinone binding
GO:0051287 NAD binding

View graph for
Molecular Function
External links
PDB RCSB:7vyf, PDBe:7vyf, PDBj:7vyf
PDBsum7vyf
PubMed35145322
UniProtF1S1A8

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