Structure of PDB 7vya Chain Q Binding Site BS01

Receptor Information
>7vya Chain Q (length=379) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NLTLNFGPGVLRLVMELSGEMVRKCDPHIGLLHRGTEKLIEYKTYLQALP
YFDRLDYVSMMCNEQAYSLAVEKLLNIQPPPRAQWIRVLFGEITRLLNHI
MAVTTHALDIGAMTPFFWMFEEREKMFEFYERVSGARMHAAYIRPGGVHQ
DLPLGLLDDIYEFSKNFSFRIDELEEMLTNNRIWRNRTVDIGVVTAEDAL
NYGFSGVMLRGSGIQWDLRKTQPYDVYDQVEFDVPIGSRGDCYDRYLCRV
EEMRQSLRIISQCLNKMPPGEIKVDDAKVSPPKRAEMKTSMESLIHHFKL
YTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPYRCKIKAPGFAHLAG
LDKMSKGHMLADVVAIIGTQDIVFGEVDR
Ligand information
>7vya Chain W (length=29) Species: 9823 (Sus scrofa) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ASKVKQDMPPPGGYGPIDYKRNLPRRGLS
Receptor-Ligand Complex Structure
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PDB7vya The coupling mechanism of mammalian mitochondrial complex I.
Resolution2.8 Å
Binding residue
(original residue number in PDB)
R166 P237 L238 L240 L241 D242 Y245 S248 S252 D256 E259 E260 R338 R342 S345 L348 N349 M351 P352 P353 G354
Binding residue
(residue number reindexed from 1)
R82 P153 L154 L156 L157 D158 Y161 S164 S168 D172 E175 E176 R254 R258 S261 L264 N265 M267 P268 P269 G270
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0048038 quinone binding
GO:0051287 NAD binding

View graph for
Molecular Function
External links
PDB RCSB:7vya, PDBe:7vya, PDBj:7vya
PDBsum7vya
PubMed35145322
UniProtF1S1A8

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