Structure of PDB 7vbz Chain Q Binding Site BS01

Receptor Information
>7vbz Chain Q (length=386) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SNLTLNFGPQHPAAHGVLRLVMELSGEMVRKCDPHIGLLHRGTEKLIEYK
TYLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIQPPPRAQWIRVLFGEI
TRLLNHIMAVTTHALDIGAMTPFFWMFEEREKMFEFYERVSGARMHAAYI
RPGGVHQDLPLGLLDDIYEFSKNFSFRIDELEEMLTNNRIWRNRTVDIGV
VTAEDALNYGFSGVMLRGSGIQWDLRKTQPYDVYDQVEFDVPIGSRGDCY
DRYLCRVEEMRQSLRIISQCLNKMPPGEIKVDDAKVSPPKRAEMKTSMES
LIHHFKLYTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPYRCKIKAP
GFAHLAGLDKMSKGHMLADVVAIIGTQDIVFGEVDR
Ligand information
>7vbz Chain W (length=29) Species: 9823 (Sus scrofa) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ASKVKQDMPPPGGYGPIDYKRNLPRRGLS
Receptor-Ligand Complex Structure
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PDB7vbz The coupling mechanism of mammalian mitochondrial complex I.
Resolution2.4 Å
Binding residue
(original residue number in PDB)
R166 P237 L238 L241 D242 Y245 S248 S252 D256 E259 R338 L348 N349 M351 P352 P353 G354
Binding residue
(residue number reindexed from 1)
R89 P160 L161 L164 D165 Y168 S171 S175 D179 E182 R261 L271 N272 M274 P275 P276 G277
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0048038 quinone binding
GO:0051287 NAD binding

View graph for
Molecular Function
External links
PDB RCSB:7vbz, PDBe:7vbz, PDBj:7vbz
PDBsum7vbz
PubMed35145322
UniProtF1S1A8

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