Structure of PDB 7oic Chain Q Binding Site BS01

Receptor Information
>7oic Chain Q (length=219) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RFLSPEFIPRRGRTDPLKFQIERKDMLERRKVLHIPEFYVGSILRVTTAD
PYASGKISQFLGICIQRSGRGLGATFILRNVIEGQGVEICFELYNPRVQE
IQVVKLEKRLDDSLLYLRDALPEYSTFDVNMKPVVQEPNQKVPVNELKVK
MKPKPWSKRWERPNFNIKGIRFDLCLTEQQMKEAQKWNQPWLEFDMMREY
DTSKIEAAIWKEIEASKRS
Ligand information
>7oic Chain A (length=1383) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccccaccuuacuaccaaaccuuagccaaacc
auuuaccaaaauaaaguauaggcgauagaaauugacuggcgcaauagaua
uaguaccgcaagggaaagaugaaaaaaccaagcauaauauagcaaggacu
aaccccuauaccuucugcauaaugaauuaacuagaaauaacuuugcaagg
agagccaaagcuaagacccccgaaaccagacgagcuaccuaagaacagcu
aaaagagcacacccgucuauguagcaaaauagugggaagauuuauaggua
gaggcgacaaaccuaccgagccuggugauagcugguuguccaagauagaa
ucuuaguucaacuuuaaauuugcccacagaaccaaauccccuuguaaauu
uaacuguuaguccaaagaggaacagcucuuuggacacuaggaaaaaaccu
uguagagagaguaaaaaauuuaacacccauaguaggccuaaaagcagcca
ccaauuaagaaagcguucaagcucaacaccaaaaaucccaaacauauaac
ugaacuccucacacccaauuggaccaaucuaucacccuauagaagaacua
auguuaguauaaguaacaugaaaacauucuccuccgcauaagccugcguc
agauacugacaauuaacagcccaauaucuacaaucaaccaacaagucauu
auuacccucacugucaacccaacacaggcaugcucauaaggaaagguuaa
aaaaaguaaaaggaacucggcaaaucuuaccccgccuguuuaccaaaaac
aucaccucuagcaucaccaguauuagaggcaccgccuuggcuccacgagg
guucagcugucucuuacuuuuaaccagugaaauugaccugcccgugaaga
ggcgggcauaacacagcaagacgagaagacccuauggagcuuuaauuuau
uaaugcaaacaguaaccugcauuaaaaauuucgguuggggcgaccucgga
gcagaacccaaccuccgagcaguacaugcuaagacuucaccagucaaagc
gaaccucaauugauccaauaacuugaccaacggaacaaguuacccuaggg
auaacagcgcaauccuauucuagaguccauaucaacaauaggguuuacga
ccucgauguuggaucaggacaucccgauggugcagccgcuauuaaagguu
cguuuguucaacgauuaaaguccuacgugaucugaguucagaccggagua
auccaggucgguuucuaucuacuuuauuccucccuguacgaaaggacaag
agaaauaaggccuacuucacaaagcgccuucccccguaaaugauaucauc
ucaacuuagauacccacacccaagaacaggguu
<<<.......<<<<...............................<....
..>...............<<.....>>..........>>.>>........
.....<<....>>.................>>>...........<<<...
....>>>...<.<........>.>.<<<<<<.........<<<.<<..<<
....>>...>>.>>>...<<.<...<<<<.<.....<<<<<.<<<..<<<
.....>>>...<<<..<<<<........>>>>.>>>....>>>.>>>>>.
..<<.......>>......>.>>>>......>.>>..<<<<<<....<<<
<....>>>><<<.<<<<<<<<<<.....<<......>>.....>>>>>>>
>>>..>>>.<<<<<<<<<<......>>>>>>>>>>.<.<<<......>>>
.>..<<<.<<<...<..............<....<<<.........>>>.
...>.......<<<......>>>...........................
>...>>>>>>........>>>>>>...<<<<<......>>>>>.......
..>>>>>><......<<..<<<....>>><<<<..<<<<........<<<
<<...>>>>>......<<<...<<<<.......................>
>>>.......>>>.....<<......>>.>>>>.....>>>>..<<<<..
.<<<<<<<<.<<.........<......<<<<<<..<<<.........>>
>...<<<<<<.............>>>>>>....<<<..>>>....>>.>>
>>.....>..>>.>>>>>>>>>>>>.>>.....>.....<<<<<......
..>>>>>.......<<..<<<.<<......<<<<.<<<<<<..<<<<<.<
<<<<<<<..........>>>>>>>>>>>>>..<<<<.....>>>><<<<<
<...........>>>>>>..<<.....<<<..<<<<.....>>>>..>>>
....>>.........<<<....>>>............>>>>..>>>>>>.
......<<<..<.<<<<<<...<<.......>>...>>>>>>...>.>>.
>.......<.<<<..<<<<<..<<.<<<<<<......>>>>>>...>>.<
<<<<.....>>>>>.....>>>>>......>>>..>....<<<<<<<...
.>>>.>>>>....>>..>>>.>>..<<<.<<<.................>
>>.>>><<<<<...<<<....>>>.>>>>>......<<<...........
.....>>>.........<<<<.......>>>>.
Receptor-Ligand Complex Structure
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PDB7oic A distinct assembly pathway of the human 39S late pre-mitoribosome.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		R83 R84 G85 R86 S141 T148 K231 R235
Binding residue
(residue number reindexed from 1)		R10 R11 G12 R13 S68 T75 K158 R162
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7oic, PDBe:7oic, PDBj:7oic
PDBsum7oic
PubMed34315873
UniProtP49406|RM19_HUMAN Large ribosomal subunit protein bL19m (Gene Name=MRPL19)

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