Structure of PDB 7oht Chain Q Binding Site BS01

Receptor Information
>7oht Chain Q (length=85) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DNVYLKLLVKLYTFLARRTDAPFNKVVLNRPPVSVSRIARALKQEGAANK
TVVVVGTVTDDARIVAADQLAVRAPKGQNTLILRG
Ligand information
>7oht Chain 1 (length=1485) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cuauuggaacaggacgucauagagggugagaaucccgugugggaccgaua
guaagaacugagagugaaaaaguacgugaaauuguugacaggccagcauc
aguuuugguggcaggauaaauccauaggaauguagcuugccugguaagua
uuauagccugugggaauacugccagcugggacugaggacugcgacguaag
ucaaggaugcuggcauugcgaguguuuggguguaaacccauacgcgaacg
uaggguccugggauaagagcauaguuccugccgaaguuucccucaggaua
gcagaagcucguaucaguuuuaugagguaaagcgaacuuuaaauauguaa
gaaguccuuguuugaacguggacauuugaaugaagagcuuuuagugggcc
auuuuugguaagcagaacuggcgaugcgggaugaaccgaacguagaguua
aggugccggaauacacgcucaucagacacacaaaagguguuaguucaucu
agacagccggacgguggccauggaagucggaauccgcuaaggagugugua
acaacucaccggccgaaugaacuagcccugaaaaggauggcgcucaagcg
uguuaccuauacucuaccgucaggguuaugcccugacgaguaggcaggcg
uggaggucagugagaagccugacaaggucgggucgaacggccucuaguga
aucagcgggggaagacccuguugagcuugacucuagguggggaguuuggg
ggcggcacaucuguuaaacgauaagcagauguccuaaggggggcucaugg
agaacagaaaucuccaguagaacaaaaggaaaagcccccuugauuuugau
uuucagugugaauacaaaccaugaaaguguggccuaucgauccuuuauag
aggugccagaaaaguuaccacagggauaacuggcuuguggcagucaagcg
uuagcgacauugcuuuugauucuucgaugucggcucuuccuaucauaccg
aagcagaauucgguaagcguuggauuguucacccacuaauagggagucug
gguuuagaccgucgugagacagguuaguuccuacugaugaauguuaccgc
aauaguaauugaacuuaguacgagaggaacaguucauucggauaauuggu
uuuugcggcugucugaucaggcaugccgcgaagcuaccauccgcuggauu
auggcugaacgccucuaagucagaauccaugcuagaacgcggugauuucu
ugcuccacacaauauagauggauacgaauaaggcguccuuguggcgucgc
ugaaccauagcaggcuagcaacggugcacuuggcggaaaggccuugggug
cuugcuggcgaauugcaaugucauuuugcguggggauaaaucauuuguau
acgacuuagauguacaacgggguauuguaagcaguagaguagccguuacg
aucugcugagauuaagccuuuguugucugauuugu
<..............((......<<<.....))>>>....>.........
.......<...>.............................<<<<<<<.<
<<<<<<<<<<<<<<.....<<<<<<<<<......<<<<<<...>>>>>>.
......>>>>>>>.>.>.>>>>>.>>>>>>>>>>........<<<....>
>>.....>>>>>>>..<<<........<<<<....>>>>...........
.....<<<..>>>.....>>>.....<<<<<<....<.<<<....>>>.>
<<.<<.<......<<<.<<<<<<.......................>>>>
...<<<<..<<<..>>>..>>>>.....>>>>>.....>.>>.>>..<<<
<.<<<<<.....>>>>>.>>>>....<<<......>>>...<<<<<<<..
<<<<(((.....<<<<<<.....<<.........<<<.<<<<<<<<<<..
.....<<<<<.<<....<<.........>>....>>.........<<...
...>>...>>>>>...>>>>>>>>>>>>>.........))).>>...>>>
>>>.>>>>..>>>>>>><<<<<<<<<...>>>>>>>>>....>>>>>>..
.<<<<<<..<<.....<<<<<<.....>>>>>>...>>.>>>>>>.....
<<<<<..<<......<<<<<.<<.<<<..<<<<<......>>>>>.....
.<.<..<<.<<<<<..........>>>>>.>>.....<<<<<<<...<<<
.<.........>.>>>.................>>>>>>>...<<<..<<
<<.......>>>>..>>>.<<<....>>>...>.>........<.....>
............>>>...>>>>>>>..............<<<<<...<<.
...>>...>>>>>.................<<<...<<<<<..<.<<<<<
<<......>>>>>>>...>.<<<.........>>>.....>>>>>..>>>
......<<<<<<<....>>>.>>>>.....>>.>>>>>....<<<<<<<<
..<<<<.<.<<<<<<...............>>>>>>.><<<<<...<<<<
...<<<<<<<<<<<....>>>>>.>>>>>>..>>>>..>>>>>.<<<<..
.<<<<<...........>>>>>...>>>>.>>>>....>>>>>>>>....
..<<<<<<.<<<.<<....<<..........<<<<<<.....>>>>>>..
....>>.......<<<<<<...<<<<<.<..<<<......>>>..>.>>>
>>.>>>>>>.............>>.>>>.>>>>>>..<<<<<.<......
.......>.....<<<<<<<<<.<<<....<<<<.<..<<<<<.>>>>>.
.>>>>>...>>>....>>>>.>>>>>..>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7oht Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Resolution4.7 Å
Binding residue
(original residue number in PDB)		K27 K31 F35 R38 R39 P61 S63 S65 R66 R69 T86 T88 D89 D90 R92
Binding residue
(residue number reindexed from 1)		K6 K10 F14 R17 R18 P32 S34 S36 R37 R40 T57 T59 D60 D61 R63
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:0043232 intracellular non-membrane-bounded organelle
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7oht, PDBe:7oht, PDBj:7oht
PDBsum7oht
PubMed34813592
UniProtP0CX49|RL18A_YEAST Large ribosomal subunit protein eL18A (Gene Name=RPL18A)

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