Structure of PDB 7kd6 Chain Q Binding Site BS01

Receptor Information
>7kd6 Chain Q (length=290) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKL
IMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKEL
GLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNHIVLNKDDNEE
CGDICNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSEC
LGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDL
HHKCCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7kd6 Single-chain insulin analogs threaded by the insulin receptor alpha CT domain.
Resolution2.6 Å
Binding residue
(original residue number in PDB)
R14 L36 L37 F64 F88 F89 F96 R118
Binding residue
(residue number reindexed from 1)
R10 L32 L33 F60 F84 F85 F92 R114
Enzymatic activity
Enzyme Commision number 2.7.10.1: receptor protein-tyrosine kinase.
External links
PDB RCSB:7kd6, PDBe:7kd6, PDBj:7kd6
PDBsum7kd6
PubMed36181268
UniProtP06213|INSR_HUMAN Insulin receptor (Gene Name=INSR)

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