Structure of PDB 7kd6 Chain Q Binding Site BS01
Receptor Information
>7kd6 Chain Q (length=290) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
GEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKL
IMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKEL
GLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNHIVLNKDDNEE
CGDICNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSEC
LGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDL
HHKCCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCP
Ligand information
>7kd6 Chain R (length=15) Species:
9606
(Homo sapiens) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
TFEDYLHNVVFVPRP
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
7kd6
Single-chain insulin analogs threaded by the insulin receptor alpha CT domain.
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
R14 L36 L37 F64 F88 F89 F96 R118
Binding residue
(residue number reindexed from 1)
R10 L32 L33 F60 F84 F85 F92 R114
Enzymatic activity
Enzyme Commision number
2.7.10.1
: receptor protein-tyrosine kinase.
External links
PDB
RCSB:7kd6
,
PDBe:7kd6
,
PDBj:7kd6
PDBsum
7kd6
PubMed
36181268
UniProt
P06213
|INSR_HUMAN Insulin receptor (Gene Name=INSR)
[
Back to BioLiP
]