Structure of PDB 6rql Chain Q Binding Site BS01

Receptor Information
>6rql Chain Q (length=476) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TFIRGPICGTDNCPSRLWRIIDGRRTCQYGHVMEGDVEFNDDEDGAGVIT
RRLNLTTNATGSFQSSQLTNSQLLQQQQRQSHKKFKKLIGHEAKLLFLKS
FQFILKRQIRWLITEMRFPKEFEHVAKIIWLKILKTINDQPQEELKLQLH
MTSTISILYLASTHLSLPVYTCDYIKWICTAKMPYFQASEILPKSWRIQL
PNYYVSILEGSISPFNGQLYNKIALTCGMIHFKEFFNSEISCQGLLLKLV
MQCALPPEFYFYTKQVIEFEETDIRNLTLWERTDERHTGRVSNHAELRVL
SYFMLTINWMLSFDRDRQYPLKWILSLTESLTQRTTTSESIGRNIVKVVY
PDKPTSSDYFQWSEEETLEFLKWMEKQFLPTDQKIARRKLYKIFPLDREA
NHDGEFNDSTHQLTFIEDLQERYAKQTPFFPPARKEAIGRLLTHIASQLL
VDFAISKEQLKDCISRIKNACLHRMN
Ligand information
>6rql Chain T (length=42) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atgaagtacctcccaactacttttcctcacacttgtactcca
Receptor-Ligand Complex Structure
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PDB6rql Molecular insight into RNA polymerase I promoter recognition and promoter melting.
Resolution2.9 Å
Binding residue
(original residue number in PDB)
L154 H157 Y210 Q225 K229 R293 T295 R297 H511
Binding residue
(residue number reindexed from 1)
L147 H150 Y203 Q218 K222 R286 T288 R290 H473
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0017025 TBP-class protein binding
GO:0046872 metal ion binding
Biological Process
GO:0001188 RNA polymerase I preinitiation complex assembly
GO:0006360 transcription by RNA polymerase I
GO:0042790 nucleolar large rRNA transcription by RNA polymerase I
Cellular Component
GO:0000120 RNA polymerase I transcription regulator complex
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0070860 RNA polymerase I core factor complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6rql, PDBe:6rql, PDBj:6rql
PDBsum6rql
PubMed31804486
UniProtP40992|RRN7_YEAST RNA polymerase I-specific transcription initiation factor RRN7 (Gene Name=RRN7)

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