Structure of PDB 6j6g Chain Q Binding Site BS01

Receptor Information
>6j6g Chain Q (length=292) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DEINEPPPNICEQCLGDEANIRMTKIPQGSECKICTLPFTLYHFKTSKRS
NNIIKTLICVRCATQRNICQCCMLDSRWHIPIQLRDHLISLVNEENVMTE
EAKNDMMKRFLSLKNVKLGGAQITSDPSEADNIVDKLKNILLRAYASVDI
SHILKKLPLNESFLKNPSTKSFFLYNIDASIPEWKITDTVSQLLGIKKWK
DGNSLSLIVNHKAKCGGLRFQSSELGERFVSKISETLVTPKGLKRGVLLI
DRFRIFIIPWSSGFSAASFGTNTAENIKLSLSLNKLIQLELG
Ligand information
>6j6g Chain E (length=103) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guucgcgaaguaacccuucguggacauuuggucaauuugaaacaauacag
agaugaucagcaguuccccugcauaaggaugaaccguuuuacaaagagau
uua
<<<<<<<<<<.....>>>>>>>>>>.........................
............<<<..<<<.....>>>...>>>................
...
Receptor-Ligand Complex Structure
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PDB6j6g Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		L43 K47 K50 R51 N53 I55 K57 M108
Binding residue
(residue number reindexed from 1)		L41 K45 K48 R49 N51 I53 K55 M106
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0017070 U6 snRNA binding
GO:0036002 pre-mRNA binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0000974 Prp19 complex
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0071006 U2-type catalytic step 1 spliceosome
GO:0071007 U2-type catalytic step 2 spliceosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6j6g, PDBe:6j6g, PDBj:6j6g
PDBsum6j6g
PubMed30879786
UniProtP38241|SLT11_YEAST Pre-mRNA-splicing factor SLT11 (Gene Name=ECM2)

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