Structure of PDB 6gsm Chain Q Binding Site BS01

Receptor Information
>6gsm Chain Q (length=141) Species: 284590 (Kluyveromyces lactis NRRL Y-1140) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TVPSVQTFGKKKSATAVAHVKAGKGLIKVNGSPITLVQPEILRFKVYEPL
LLVGLDKFANIDIRVKVTGGGHVSQVYAIRQAIAKGLVAYHQKFVDEQSK
NELKKAFTSYDRTLLIADSRRPEPKKFGGRGARSRFQKSYR
Ligand information
>6gsm Chain 2 (length=1798) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguuccuuuacuacauggauaucug
ugguaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaagag
auguauuuauuagauaaaaaaucaaugucuucggacuccuugaugauuca
uaauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaaa
uuucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuuc
aacggguaacggggaauaaggguucgauuccggagagggagccugagaaa
cggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaauccua
auucagggagguagugacaauaaauaacgauacagggcccauucgggucu
uguaauuggaaugaguacaauguaaauaccuuaacgaggaacaacuggag
ggcaagucuggugccagcagccgcgguaauuccagcuccaguagcguaua
uuaaaguuguugcaguuaaaaagcucguaguugaacuuugggucugguug
uccgguccgacuuuaugucgcgcacugguuuucaaccggaucuuuccuuc
uggcuaaccuguacuccuugugggugcaggcgaaccaggacuuuuacuuu
gaaaaaauuagaguguucaaagcaggcgaaagcucgaauauauuagcaug
gaauaauggaauaggacguuugguucuauuuuguugguuucuaggaccau
cguaaugauuaauagggacggucgggggcaucaguauucaauugucagag
gugaaauucuuggauuuauugaagacuaacuacugcgaaagcauuugcca
aggacguuuucauuaaucaagaacgaaaguuaggggaucgaagaugauca
gauaccgucguagucuuaaccauaaacuaugccgacuagggaucgggugg
uguuuuucuuaugacccacucggcaccuuacgagaaaucaaagucuuugg
guucuggggggaguauggucgcaaggcugaaacuuaaaggaauugacgga
agggcaccaccaggaguggagccugcggcuuaauuugacucaacacgggg
aaacucaccagguccagacacaauaaggauugacagauugagagcucuuu
cuugauuuugugggugguggugcauggccguucuuaguugguggagugau
uugucugcuuaauugcgauaacgaacgagaccuuaaccuacuaaauaggg
uugcuggcacuugccgguugacucuucuuagagggacuaucgguuucaag
ccgauggaaguuugaggcaauaacaggucugugaugcccuuagacguucu
gggccgcacgcgcgcuacacugacggagccagcgaguacaaccuuggccg
agaggucuggguaaucuugugaaacuccgucgugcuggggauagagcauu
guaauuauugcucuucaacgaggaauuccuaguaagcgcaagucaucagc
uugcguugauuacgucccugcccuuuguacacaccgcccgucgcuaguac
cgauugaauggcuuagugaggccucaggauuugcuuagagaagggggcaa
cuccaucucagagcgaagaaucuggucaaacuuggucauuuagaggaacu
aaaagucguaacaagguuuccguaggugaaccugcggaaggaucauua
...<<<<<...[[[[>>>>>[[[[.((((((................[[[
.[[[...<....<<....<<..........>>...>>.>.......{{..
......[[[......{{....[[[{...............<<.....<<.
.<.......>..>>......>>........<<<<<............>>>
>>{..[[.((((......<<<<<<<<.<......>...............
))))]].....}...<<<<..<<<.....>>>.>>>>..}.]]]...}}.
...]]].<<<....<<<....<<<<<<<<.......>>>>>>>>>>>...
...>>>...<<<.<<<<....>>>>....>>>.}}.<<.<<<........
..>>>.>>.<.<......>.>...]]]]]].........<<<....<<<.
....>>>..>>>................<..<<<<<.<.......>..>>
>>>...>.......<<..<...........>.>.>.........<<<<<(
(......<<<<.....<<..))>>.......>>>>.>>>>>..))))))]
]]].........[[[{{.......{{...[[[.{{.....<<<<<<<<<<
.<<<<<.<<<.......>>>...>>>>>....>>>>>>>>>>.....<<<
<<<......<.................>......>>>>>>...<<<<<.<
<......<<<...<.......>..<<<....>>>....>>.>....>>.>
>..>>>.........[[[..(((((((.....>>>>>>>>..))))))).
]]].....}}....<<<<<<.<<...<<<<..<<..<<<<<<.<...<<.
.......>>......>.>>>>>>..>>.......<<....>>...>>>>.
..>>>>>.>>>...]]]...}}......<<<<<<<...<...<<<<....
.....>>>>...>>>>>>>>..........<<<.<<.<<<..<<<<<<<<
.<<.<.......>>>>>>>>>>>..>>>...<<..}}>>...>>.....>
>>.]]].<<<......<.<......>.>....>>>..]]]]..<<<<<.<
<<<<<<..<<.<<<<<<..<<<.<<<<<<......<<........>>...
.......<<<<<.<....<<<<<........<<..<<........>>..>
>......>>>>>...<<.<<<..<<.<<<<<<....<<<.<<<<......
>>...<<<......>>>...>>.>>>....<<<<<.<<..<<<<....<<
<<<.<<<<....>>>>.>.>>>>....>>>>.>>....<<<<<<.....>
>>>>>.......>>>>>....>>>.>>>.....>>>>>>>.....>.>>>
>>...>>.>>>>.>>>.....<<<<<<<......<<.....<<<..<<<.
...>>>..>>>....>>.......>>>>>>>......<....<<<<<<..
........>>>>>>....>.....>>>>>>....<<<<<<<<.......>
>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<..<<<<.<
<....<<<<<<<<.<<<..<<<<......<<<<<<.<<............
......>>...>>>>>>......>>>>..>>>.>>>>>>>>...>>.>>>
>...>.>>...>.....<<<<<<<<<....>>>>>>>>>.........
Receptor-Ligand Complex Structure
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PDB6gsm Large-scale movement of eIF3 domains during translation initiation modulate start codon selection.
Resolution5.15 Å
Binding residue
(original residue number in PDB)
T3 Q8 T9 F10 K12 K14 S15 H21 K26 L28 K30 Q40 P41 E42 T70 G71 G72 G73 V75 S76 I118 S121 R122 R123 E125 P126 K127 K128 F129 G130 R132 A134 R135 S136 R137 F138 Q139 K140 Y142 R143
Binding residue
(residue number reindexed from 1)
T1 Q6 T7 F8 K10 K12 S13 H19 K24 L26 K28 Q38 P39 E40 T68 G69 G70 G71 V73 S74 I116 S119 R120 R121 E123 P124 K125 K126 F127 G128 R130 A132 R133 S134 R135 F136 Q137 K138 Y140 R141
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6gsm, PDBe:6gsm, PDBj:6gsm
PDBsum6gsm
PubMed34648019
UniProtQ875N2|RS16_KLULA Small ribosomal subunit protein uS9 (Gene Name=RPS16)

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