Structure of PDB 6ff4 Chain Q Binding Site BS01

Receptor Information
>6ff4 Chain Q (length=138) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KVKRSRKAPPDGWELIEPTLDELDQKMREAETEPHEGKRKVESLWPIFRI
HHQKTRYIFDLFYKRKAISRELYEYCIKEGYADKNLIAKWKKQGYENLCC
LRCIQTRDTNFGTNCICRVPKSKLEVGRIIECTHCGCR
Ligand information
>6ff4 Chain 6 (length=95) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gugcucgcuucggcagcacauauacuaaaauuggaacgauacagagaaga
uuagcauggccccugcgcaaggaugacacgcaaauucgugaagcg
<<<<<.<<....>>>>>>>...............................
......<<...<<<.....>>>....>>.................
Receptor-Ligand Complex Structure
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PDB6ff4 Structure and Conformational Dynamics of the Human Spliceosomal BactComplex.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		G39 R41 Q95 G96 E98 T111 N112 T115 N116 C117 I118 R120 V121 P122 K125 T135 H136 R140
Binding residue
(residue number reindexed from 1)		G37 R39 Q93 G94 E96 T109 N110 T113 N114 C115 I116 R118 V119 P120 K123 T133 H134 R138
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0016922 nuclear receptor binding
GO:0030374 nuclear receptor coactivator activity
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0045893 positive regulation of DNA-templated transcription
GO:2000825 positive regulation of androgen receptor activity
Cellular Component
GO:0000785 chromatin
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005681 spliceosomal complex
GO:0071007 U2-type catalytic step 2 spliceosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ff4, PDBe:6ff4, PDBj:6ff4
PDBsum6ff4
PubMed29361316
UniProtP41223|BUD31_HUMAN Protein BUD31 homolog (Gene Name=BUD31)

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