Structure of PDB 5zjk Chain Q Binding Site BS01

Receptor Information
>5zjk Chain Q (length=204) Species: 1736763 (Myroides sp. CSLB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GAVVRSTKWPNGSVITVGLYGGTPYVRSKVKQYAQEWSNYANITFNFVES
GTPQIRVTFTQGAGSYSYLGTQALSIPSNEETMNFGWFDDSTSDTEFSRT
VIHEFGHALGMIHEHQHPLTNIPWDKNKVYAYYAGYPNYWSKKDVDNNLF
ATYSTTQTQYSAYDTQSIMHYSISSALTTNGFSVGNNSVLSATDKQFIAT
VYPR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5zjk Chain Q Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5zjk Crystal structure of mature myroilysin and implication for its activation mechanism.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		H140 H144 H150 Y208
Binding residue
(residue number reindexed from 1)		H103 H107 H113 Y171
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:5zjk, PDBe:5zjk, PDBj:5zjk
PDBsum5zjk
PubMed31785296
UniProtA0A0P0DZ84

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