Structure of PDB 5nrl Chain Q Binding Site BS01

Receptor Information
>5nrl Chain Q (length=220) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KRRKTEKPSLSQLKSQVPYPQIIEWYDCDARYPGLLASIKCTKNVIPVPS
HWQSKKEYLSGRSLLGKRPFELPDIIKKTNIEQMRSTLPALDLDYKKLHD
VFFKIGANWKPDHLLCFGDVYYENRNLFEETNWKRMVDHKRPGRISQELR
AIMNLPEGQLPPWCMKMKDIGLPTGYPDLKIAGLNWDITNLKGDVYGKII
PNHHRNYFGALISFETPEFE
Ligand information
>5nrl Chain 2 (length=155) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaaucucuuugaaguguaguaucuguucuuuucaguguaacaacugaaau
gaccuaggcucauacacauuuuuuggcaggacgggaagaggagacgucgc
gacccucgcacgagucguucuugacuuggucgcuugauguuucuucuucc
cguuc
Receptor-Ligand Complex Structure
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PDB5nrl Structure of a pre-catalytic spliceosome.
Resolution7.2 Å
Binding residue
(original residue number in PDB)		W149 D153 Q177
Binding residue
(residue number reindexed from 1)		W25 D29 Q53
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0000245 spliceosomal complex assembly
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:1903241 U2-type prespliceosome assembly
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005684 U2-type spliceosomal complex
GO:0005686 U2 snRNP
GO:0071004 U2-type prespliceosome
GO:0071011 precatalytic spliceosome
GO:0071013 catalytic step 2 spliceosome

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Biological Process
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Cellular Component
External links
PDB RCSB:5nrl, PDBe:5nrl, PDBj:5nrl
PDBsum5nrl
PubMed28530653
UniProtQ02554|CUS1_YEAST Cold sensitive U2 snRNA suppressor 1 (Gene Name=CUS1)

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