Structure of PDB 5lqw Chain Q Binding Site BS01

Receptor Information
>5lqw Chain Q (length=791) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NVEGIHDLMFFKPSDHKYFADVISKKKERTLSMLLLKIKTASRRTSMRIL
TDKAVTFGPEMIFNRLLPILLDRSLEDQERHLMIKTIDRVLYQLGDLTKP
YVHKILVVAAPLLIDEDPMVRSTGQEIITNLSTVAGLKTILTVMRPDIEN
EDEYVRNVTSRAAAVVAKALGVNQLLPFINAACHSRKSWKARHTGIKIVQ
QIGILLGIGVLNHLTGLMSCIKDCLMDHVPVRIVTAHTLSTLAENSYPYG
IEVFNVVLEPLWKGIRSHVLSSFLKAVGSMIPLMDPEYAGYYTTEAMRII
RREFDSDEMKKTILLVLQKCSAVESITPKFLREEIAPEFFQKFWVRRVAL
DRPLNKVVTYTTVTLAKKLGSYTIDKLLTPLRDEAEPFRTMAVHAVTRTV
NLLGTADLDERLETRLIDALLIAFQEQTNSDSIIFKGFGAVTVSLDIRMK
PFLAPIVSTILNHLKHKTPLVRQHAADLCAILIPVIKNCHEFEMLNKLNI
ILYESLGEVYPEVLGSIINAMYCITSVMDLDPINQILPTLTPILRNKHRK
VEVNTIKFVGLIGKLPKEWMRICFELLELLKSTNKEIRRSANATFGFIAP
HDVLVALLNNRVCTAVAIGIVAKVCGPYNVLPVIMNEYTTPETNVQNGVL
KAMSFMFEYIGNMSKDYIYFITPLLEDALTDLVHRQTASNVITHLALNCS
GTGHEDAFIHLMNLLIPNIFETSPHAIMRILEGLEALSQALGPGLFMNYI
WAGLFHPAKNVRKAFWRVYNNMYVMYQDAMVPFYPVTPDNN
Ligand information
>5lqw Chain 2 (length=81) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaaucucuuugccuuuuggcuuagaucaaguguaguaucuguucuuuuca
guguaacaacugaaaugaccucaaugaggcu
...............................................<<<
<<......>>>>>.....<<<<...>>>>..
Receptor-Ligand Complex Structure
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PDB5lqw Molecular architecture of the Saccharomyces cerevisiae activated spliceosome
Resolution5.8 Å
Binding residue
(original residue number in PDB)		A179 S892 A927 K928 N929
Binding residue
(residue number reindexed from 1)		A41 S723 A758 K759 N760
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0005515 protein binding
Biological Process
GO:0000245 spliceosomal complex assembly
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:1903241 U2-type prespliceosome assembly
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005684 U2-type spliceosomal complex
GO:0005686 U2 snRNP
GO:0071004 U2-type prespliceosome
GO:0071013 catalytic step 2 spliceosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5lqw, PDBe:5lqw, PDBj:5lqw
PDBsum5lqw
PubMed27562955
UniProtP49955|SF3B1_YEAST U2 snRNP component HSH155 (Gene Name=HSH155)

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