Structure of PDB 3j7y Chain Q Binding Site BS01

Receptor Information
>3j7y Chain Q (length=204) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RFLSPEFIPRRGRTDPLKFQIERKDMLERRKVLHIPEFYVGSILRVTTAD
PYASGKISQFLGICIQRSGRGLGATFILRNVIEGQGVEICFELYNPRVQE
IQVVKLEKRLDDSLLYLRDALPEYQKVPVNELKVKMKPKPWSKRWERPNF
NIKGIRFDLCLTEQQMKEAQKWNQPWLEFDMMREYDTSKIEAAIWKEIEA
SKRS
Ligand information
>3j7y Chain A (length=1472) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccagcaaccuuagcc
aaaccauuuacauaaaguauaggcgauagaaauuguggcgcaauagauau
aguaccgcaagggaaagaugaaaaauuauaaccaagcauaauauagcaag
gacuaaccccuauaccuucugcauaaugaauuaacuagaaauaacuuugc
aaggagagccaaagcuaagacccccgaaaccagacgagcuaccuaagaac
agcuaagagcacacccgucuauguagcaaaauagugggaagauuuauagg
uagaggcgacaaaccuaccgagccuggugauagcugguuguccaagauag
aaucuuaguucaacuuuaaauuugcccacagaaccaaauccccuuguaaa
uuuaacuguuaguccaaagaggaacagcucuuuggacacuaggaaaaaac
cuuguagagagaguaaaaaauuuaacacccauaguaggccuaaaagcagc
caccaauuaagaaagcguucaagcucaacaccaaaaaucccaaacauaua
acugaacuccucacacccaauuggaccaaucuaucacccuauagaagaac
uaauguuaguauaaguaacaugaaaacauucuccuccgcauaagccugcg
ucagaucacacugacaauuaacagcccaauaucuacaaucaaccaacaag
ucauuauuacccucacugucaacccaacacaggcaugcucauaaggaaag
guuaaaaaaaguaaaaggaacucggcaaaucuuaccccgccuguuuacca
aaaacaucaccucuagcaucaccaguauuagaggcaccgccugcccagug
acacauguuuaacggccgcgguuaaccgugcaaagguagcauaaucacuu
guuccuuaaauagggaccuguaugaauggcuccacgaggguucagcuguc
ucuuacuuuuaaccagugaaauugaccugcccgugaagaggcgggcauaa
cacagcaagacgagaagacccuauggagcuuuaauuuauuaaugcaaaca
guaaccugcauuaaaaauuucgguuggggcgaccucggagcagaacccaa
ccuccgagcaguacaugcuaagacuucaccagucaaagcgaaccucaauu
gauccaauaacuugaccaacggaacaaguuacccuagggauaacagcgca
auccuauucuagaguccauaucaacaauaggguuuacgaccucgauguug
gaucaggacaucccgauggugcagccgcuauuaaagguucguuuguucaa
cgauuaaaguccuacgugaucugaguucagaccggaguaauccaggucgg
uuucuaucuacuuuauuccucccuguacgaaaggacaagagaaauaaggc
cuacuucacaaagcgccuucccccguaaaugauaucaucucaacuuagau
acccacacccaagaacaggguu
<<<.......<<<<....................................
<......>.....<.....<<.....>>....>...>>.>>.........
....<<....>>......................>>>...........<<
<.......>>>...<.<........>.>.<<<<<<.........<<<.<<
..<<....>>...>>.>>>...<<.<...<<<<.<.....<<<<<.<<<.
.<<<...>>>...<<<..<<<<........>>>>.>>>....>>>.>>>>
>...<<.......>>......>.>>>>......>.>>..<<<<<<....<
<<<....>>>><<<.<<<<<<<<<<.....<<......>>.....>>>>>
>>>>>..>>>.<<<<<<<<<<......>>>>>>>>>>.<.<<<......>
>>.>..<<<.<<<...<..............<......<.........>.
.....>.......<<<......>>>.........................
..>...>>>>>>........>>>>>>...<<<<<......>>>>>.....
....>>>>>><......<<..<<<....>>><<<<..<<<<........<
<<<<......>>>>>......<<<...<<<<...................
....>>>>.......>>>.....<<......>>.>>>>.....>>>>..<
<<<...<<<<<<<..<<.........<......<<<<<<..<<<......
...>>>...<<<<<<.............>>>>>>....<<<.<<<..<<<
<<....>>>..>>>>><<<<<....>>>>>........<...........
<<<<<<.....>>>>>>.....>....>>>....>>.>>>>.....>..>
>..>>>>>>>>>>>.>>.....>.....<<<<<........>>>>>....
...<<..<<<.<<......<<<<.<<<<<<..<<<<<.<<<<<<<<....
......>>>>>>>>>>>>>..<<<<.....>>>><<<<<<..........
.>>>>>>..<<.....<<<..<<<<.....>>>>..>>>....>>.....
....<<<....>>>............>>>>..>>>>>>.......<<<..
<.<<<<<<...<<.......>>...>>>>>>...>.>>.>.......<.<
<<.<<<<<<..<<.<<<<<<......>>>>>>...>>.<<<<<.....>>
>>>.....>>>>>..>...>>>..>....<<<<<<<....>>>.>>>>..
..>>..>>>.>>..<<<.<<<.................>>>.>>><<<<<
...<<<....>>>.>>>>>......<<<................>>>...
......<<<<.......>>>>.
Receptor-Ligand Complex Structure
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PDB3j7y Structure of the large ribosomal subunit from human mitochondria.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		R83 R84 G85 R86 S141 G146 T148 K231 R232
Binding residue
(residue number reindexed from 1)		R10 R11 G12 R13 S68 G73 T75 K143 R144
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3j7y, PDBe:3j7y, PDBj:3j7y
PDBsum3j7y
PubMed25278503
UniProtP49406|RM19_HUMAN Large ribosomal subunit protein bL19m (Gene Name=MRPL19)

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