Structure of PDB 6gsl Chain P8 Binding Site BS01

Receptor Information
>6gsl Chain P8 (length=47) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKRTWQPNRRKRAKTHGFRARMRTPGGRKVLKRRRQKGRWRLTPAVR
Ligand information
>6gsl Chain 1H (length=2895) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aagaugguaagggcccacgguggaugccucggcacccgagccgaugaagg
acguggcuaccugcgauaagccagggggagccgguagcgggcguggaucc
cuggauguccgaaugggggaacccggccggcgggaacgccggucaccgcg
cuuuuugcgcggggggaaccuggggaacugaaacaucucaguacccagag
gagaggaaagagaaaucgacucccugaguagcggcgagcgaaaggggacc
agccuaaaccguccggcuuguccgggcggggucguggggcccucggacac
cgaauccccagccuagccgaagcuguugggaagcagcgccagagagggug
aaagccccguaggcgaaagguggggggauaggugaggguacccgaguacc
ccgugguucguggagccaugggggaaucugggcggaccaccgccuaaggc
uaaguacuccgggugaccgauagcgcaccaguaccgugagggaaagguga
aaagaaccccgggaggggagugaaauagagccugaaaccgugggcuuaca
agcagucacggccccgcaagggguuguggcgugccuauugaagcaugagc
cggcgacucacggucgugggcgagcuuaagccguugaggcggaggcguag
ggaaaccgaguccgaacagggcgcaaacgggggccgaaaaguccgcggcc
guggacccgaaaccgggcgagcuagcccuggccagggugaagcuggggug
agacccaguggaggcccgaaccggugggggaugcaaaccccucggaugag
cuggggcuaggagugaaaagcuaaccgagcccggagauagcugguucucc
ccgaaaugacuuuagggucagccucaggcgcugacuggggccuguagagc
acugauagggcuagggggcccaccagccuaccaaacccugucaaacuccg
aagggucccagguggagccugggagugagggcgcgagcgauaacguccgc
guccgagcgcgggaacaaccgagaccgccagcuaaggcccccaagucugg
gcuaagugguaaaggauguggcgccgcgaagacagccaggauguuggcuu
agaagcagccaucauuuaaagagugcguaauagcucacuggucgaguggc
gccgcgccgaaaaugaucggggcuuaagcccagcgccgaagcugcggguc
ugggggaugaccccaggcgguaggggagcguucccgaugccgaugaaggc
cgacccgcgagggcggcuggagguaagggaagugcgaaugccggcaugag
uaacgauaaagagggugagaaucccucucgccguaagcccaaggguuccu
acgcaauggucgucagcguaggguuaggcgggaccuaaggugaagccgaa
aggcguagccgaagggcagccgguuaauauuccggcccuucccgcaggug
cgauggggggacgcucuaggcuagggggaccggagccauggacgagcccg
gccagaagcgcagggugggagguaggcaaauccgccucccaacaagcucu
gcgugguggggaagcccguacgggugacaaccccccgaagccagggagcc
aagaaaagccucuaagcacaaccugcgggaacccguaccgcaaaccgaca
caggugggcgggugcaagagcacucaggcgcgcgggagaacccucgccaa
ggaacucugcaaguuggccccguaacuucgggagaaggggugcucccugg
ggugaugagccccggggagccgcagugaacaggcucuggcgacuguuuac
caaaaacacagcucucugcgaacucguaagaggagguauagggagcgacg
cuugcccggugccggaaggucaaggggaggggugcaagccccgaaccgaa
gccccggugaacggcggccguaacuauaacgguccuaagguagcgaaauu
ccuugucggguaaguuccgaccugcacgaaaagcguaacgaccggagcgc
ugucucggcgagggacccggugaaauugaacuggccgugaagaugcggcc
uacccguggcaggacgaaaagaccccguggagcuuuacugcagccuggug
uuggcucuuggucgcgccugcguaggauaggugggagccugugaaccccc
gccuccgggugggggggaggcgccggugaaauaccacccuggcgcggcug
ggggccuaacccucggauggggggacagcgcuuggcgggcaguuugacug
gggcggucgccuccuaaaagguaacggaggcgcccaaagguccccucagg
cgggacggaaauccgccggagagcgcaaggguagaagggggccugacugc
gaggccugcaagccgagcaggggcgaaagccgggccuagugaaccggugg
ucccguguggaagggccaucgaucaacggauaaaaguuaccccggggaua
acaggcugaucucccccgagcguccacagcggcggggagguuuggcaccu
cgaugucggcucgucgcauccuggggcugaagaaggucccaaggguuggg
cuguucgcccauuaaagcggcacgcgagcuggguucagaacgucgugaga
caguucggucucuauccgccacgggcgcaggaggcuugaggggggcucuu
ccuaguacgagaggaccggaagggacgcaccucugguuucccagcugucc
cuccaggggcauaagcuggguagccaugugcggaagggauaaccgcugaa
agcaucuaagcgggaagcccgccccaagaugaggccucccacggcgucaa
gccgguaaggacccgggaagaccacccgguggaugggccggggguguaag
cgccgcgaggcguugagccgaccggucccaaucguccgaggucuu
.<<<......<<<<<<<<<<<.....<<..<<<<<<<<<<<<......<<
<<<<.((..((.>>>.....<<<<<<<..<<<))..)).>>>.....>>>
>>>>...>>>....<<<....>>><<<<<<<<....>>>>>>>>.<<<<<
<.....>>>>>>.>>...<<<<<<.....<......>......>>>>>.>
.........<<....>>...<<<<<.....<<.....>>....>>>>>..
.<<<....<<<<<<<<.....>>>>>>>>......<<<<<<<<<....<<
<...<<<<<.<<<<.<<<...<<<<<......>>>>>((......<<<..
...))>>>...>>>...>>>>..>>>>>..>>>>>>>>>.>>>.....<<
<<<<<<<.......>>>>>>>>>......<<<<<..((((>>>>>..>>>
......>>.>>>>>>.>>...............<<....>>....>>...
......<<<<....>>>>..................>>>>>>>>>>>...
....<<<<<<<<<<<....>>>>>>>>>>>...<............>.<<
<<<<....<<<<<<<<<<<<<..<<<...<<<.....>>>...>>>...<
<....>>..<<<<.....>>>>.....<<.....>>....>>>>>>>>>>
>>>..<<.<...<<<<<<.....<<<<<<<<<..<<<....<<<<<<...
...>>>>>>.....>>>...<<<..<<<<........>>>>.>>>....>
>>>>>>>>...<<<.....>>>......>>>>>>......>.>>..<<<<
<<....<<<<<....>>>>><<<<<<<<<.....<<<<<<<<<...<<<.
..<<<<<<<<.<.<<<<<<......>>>>.>>.>.>>>>>>>>..>>.>.
..>>>>>>>>>.....>>>>>>>.>>..<<<<<<<.<<......>>.>>>
>>>>.....<<<......>>>...<<<<.<<<...<<<(((.....<<<<
<<...........<<..<<<<<<<<<........<<<<<.<....<<<<.
......>>>>.....>........<<......>>...>>>>>....>>>>
>>>>>.>>..........)))......>>>>>>.>>>...>>>>>>><<<
<<<<<.....>>>>>>>>....>>>>>>..<<<<<...<<<......<<<
<<.<<<....>>>>>>>>...>>>..>>>>>........>>>>>><....
..<<.....<<<<<<.......>>>>>><<<<....<<<<<.<<...<<<
<<<...<<.....>>.>>>>>>....((<<<<.<<...<<<...<<<...
.>>>...>>>...>>...<<<<<........>>>>>))<<<<<<<<<<<<
<...<<<<....<<<<<.<<<..<<<<<.<<<<.<<..[[[[...>>>>>
><<<...<<<<<<<<<<<<<<<<.<<.....>>>>>>>>>.....>>>>>
>>>>..>>><...<<<<....>>>>.....>>>>>>...>>>..>>>>>.
........>>>>...>>...>>>>>>>>>>>>>>>..>>.....<<....
..>>>>>>>.<<<<<....>>>>>..>>>>..<<<<....<<<<<<<<.<
<.........<.....<<<<<.....<..>......>>>>><<<<<<<<<
<<<.....>>>>>>>>>>>>............<<<<<<<<<..<<<....
.....>>>..<<<<<<<.....<<<....>>>.......>>>>>>>.<<<
<<.<<<..<<<<<<<..<<<...<<...<<<<<....>>>>>...>>...
>>>>>>>>..>>>>><<<<<<.......>>>>>>........<.......
....<<<<<<.....>>>>>>.....>....>>>>>..>>.>>>>>>>..
>..>>.>>>>>>>>.>>>>>>.....>.....<<<<<........>>>>>
..<<<<<<<<.<<<.........<<<<.<<<<<<..<<<<<.<<<.<<<<
<.<<<<<<.<<<<<<<<<...........<<...<..<<......<<<<<
<<<....>>>>>>>>...>>.............>..>>..>>>>>>>>>.
>>>>>>...<<<<<....>>>>>....>>>>>.>>>..>>>>>..<<<<.
....>>>><<<<<<...........>>>>>>..<<...<<<<<<<...<<
<<<<.......>>>>>>.....<<...(((>>....>>>>>>>...<<<<
..<<<......>>>..>>>>.<<<....>>>.>>))).......<<<<<<
<.<<..))))..>>>>>>>>>.............>>>>..>>>>>>....
...<<<<..<<<<<<<...<<.......>>...>>>>>>>...>>>.>..
.....<<<<<.<<<<<<..<<<<<<<<<......>>>>>>>..>>.<<<<
<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>
>.>>>>........>>>>>>>>>>>....<<<<<<<...<<<<..<<<<<
<<...............>>>>>>>.<<<<<...<<<<...<<<<<<<<<<
<]]]]>>>>>>...>>>>>...>>>>.>>>>>...<<<....<<<<<...
........>>>>>....>>>.>>>>.......>>>>>>>..<<.......
..>>....<<<<<<<<<.......>>>>>....<<<<<<<<.<<<....<
<<<<....>>>>>...>>>..>>>>>.>>>...>>>>....>>>.
Receptor-Ligand Complex Structure
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PDB6gsl Tautomeric G•U pairs within the molecular ribosomal grip and fidelity of decoding in bacteria.
Resolution3.16 Å
Binding residue
(original residue number in PDB)
M1 K2 R3 T4 W5 Q6 P7 N8 R9 R10 K11 R12 A13 K14 H16 G17 F18 R19 R21 P25 G26 K29 V30 K32 R33 R34 R35 K37 G38 R39 W40 R41
Binding residue
(residue number reindexed from 1)
M1 K2 R3 T4 W5 Q6 P7 N8 R9 R10 K11 R12 A13 K14 H16 G17 F18 R19 R21 P25 G26 K29 V30 K32 R33 R34 R35 K37 G38 R39 W40 R41
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6gsl, PDBe:6gsl, PDBj:6gsl
PDBsum6gsl
PubMed29931292
UniProtP80340|RL34_THET8 Large ribosomal subunit protein bL34 (Gene Name=rpmH)

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